Objective Pulmonary fibrosis (PF) is a severe extra‐articular manifestation of rheumatoid arthritis (RA). This study aimed to externally validate a genetic risk score (GRS) and a combined risk score (CRS) for predicting the risk of RA‐associated PF in an independent cohort of patients with early RA.
Mikael Brink +3 more
wiley +1 more source
Covariate-adjusted construction of gene regulatory networks using a combination of generalized linear model and penalized maximum likelihood. [PDF]
Chatrabgoun O +5 more
europepmc +1 more source
Objective Relapsing polychondritis (RP) is a rare disease defined by recurrent cartilaginous inflammation. Anti–collagen II (Col2) antibodies have been proposed as a diagnostic biomarker for RP, but their performance characteristics are not well defined.
Karyssa Stonick +6 more
wiley +1 more source
Longitudinal impact of different treatment sequences of second-generation antipsychotics on metabolic outcomes: a study using targeted maximum likelihood estimation. [PDF]
Feng Y +6 more
europepmc +1 more source
BayesAge: A maximum likelihood algorithm to predict epigenetic age. [PDF]
Mboning L +4 more
europepmc +1 more source
Guidelines and Best Practices for the Use of Targeted Maximum Likelihood and Machine Learning When Estimating Causal Effects of Exposures on Time-To-Event Outcomes. [PDF]
Talbot D +13 more
europepmc +1 more source
Revisiting the Briggs Ancient DNA Damage Model: A Fast Maximum Likelihood Method to Estimate Post-Mortem Damage. [PDF]
Zhao L +4 more
europepmc +1 more source
Maximum Likelihood Estimation for Unrooted 3-Leaf Trees: An Analytic Solution for the CFN Model. [PDF]
Hill M, Roch S, Rodriguez JI.
europepmc +1 more source
A novel maximum likelihood based probabilistic behavioral data fusion algorithm for modeling residential energy consumption. [PDF]
Bhowmik T, Iraganaboina NC, Eluru N.
europepmc +1 more source
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The maximum likelihood method is a popular statistical inferential procedure widely used in many areas to obtain the estimates of the unknown parameters of a population of interest. This chapter gives a brief description of the important concepts underlying the maximum likelihood method, the definition of the key components, the basic theory of the ...
Shuying, Yang, Daniela, De Angelis
openaire +3 more sources

