Results 261 to 270 of about 2,034,768 (362)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Guidelines and Best Practices for the Use of Targeted Maximum Likelihood and Machine Learning When Estimating Causal Effects of Exposures on Time-To-Event Outcomes. [PDF]

Stat Med
Talbot D, Diop A, Mésidor M, Chiu Y, Sirois C, Spieker AJ, Pariente A, Noize P, Simard M, Luque Fernandez MA, Schomaker M, Fujita K, Gnjidic D, Schnitzer ME.   +13 more
europepmc   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Revisiting the Briggs Ancient DNA Damage Model: A Fast Maximum Likelihood Method to Estimate Post-Mortem Damage. [PDF]

Mol Ecol Resour
Zhao L, Henriksen RA, Ramsøe A, Nielsen R, Korneliussen TS.   +4 more
europepmc   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

Advanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur, Faruk Kaya, Bora Derin, Mustafa Lütfi Öveçoğlu, Ju Li, Duygu Ağaoğulları   +5 more
wiley   +1 more source

BayesAge: A maximum likelihood algorithm to predict epigenetic age. [PDF]

Front Bioinform
Mboning L, Rubbi L, Thompson M, Bouchard LS, Pellegrini M.   +4 more
europepmc   +1 more source

Anomaly Detection Method for Hybrid Workpieces Using Dynamic Time Warping

Advanced Engineering Materials, EarlyView.
Monitoring of hybrid workpieces: when machining hybrid workpieces, unavoidable axial deviations of the material transition zone cause temporal shifts in the process force signals. A new anomaly detection method based on dynamic time warping is proposed to detect material defects.
Berend Denkena, Benjamin Bergmann, Heinrich Klemme, Miriam Handrup   +3 more
wiley   +1 more source

Correction: The Targeted Maximum Likelihood estimation to estimate the causal effects of the previous tuberculosis treatment in Multidrug-resistant tuberculosis in Sudan. [PDF]

PLoS One
Elduma AH, Holakouie-Naieni K, Almasi-Hashiani A, Foroushani AR, Ali HMH, Adam MAM, Elsony A, Mansournia MA.   +7 more
europepmc   +1 more source

Icephobic Gradient Polymer Coatings Coupled with Electromechanical De‐icing Systems: A Promising Ice Repellent Hybrid System

Advanced Engineering Materials, EarlyView.
A hybrid system for de‐icing made of gradient polymer coatings, deposited on aluminum coupled with an electromechanical system, is demonstrated as an effective and durable strategy for reducing drastically ice adhesion. The system is capable of detaching ice blocks over the coating in less than 1 s, regardless of the ice type and covered area ...
Gabriel Hernández Rodríguez, Giulia Gastaldo, Luca Stendardo, Younes Rafik, Jason Pothin, Marc Budinger, Carlo Antonini, Valérie Pommier‐Budinger, Anna Maria Coclite   +8 more
wiley   +1 more source

A novel maximum likelihood based probabilistic behavioral data fusion algorithm for modeling residential energy consumption. [PDF]

PLoS One
Bhowmik T, Iraganaboina NC, Eluru N.
europepmc   +1 more source