Results 161 to 170 of about 4,220,209 (306)

Marginal Maximum Likelihood Estimation of Item Response Models in R [PDF]

Item response theory (IRT) models are a class of statistical models used by researchers to describe the response behaviors of individuals to a set of categorically scored items.
Matthew S. Johnson
core  

Aggregation-Sensitive Mortality Associations and Firth Penalized Logistic Regression After Hip Fracture Surgery: A Retrospective Cohort Study. [PDF]

J Clin Med
Demir O.
europepmc   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Comparative Efficacy of Medial Rectus Plication Versus Resection for Exotropia: A Systematic Review and Meta-Analysis. [PDF]

Cureus
Ismail MM, Medhat Ahmed A, Ali Youssef Y, Alsharabi O, Osama Taha L, Gamal Mohamed M, Khaled Mohamed M, Abdelbaset Elsayed Mohamed Elkasabi A, Ali Mohammed Amrein E, Abdallah Alaswad M, Ayman Nomier A, Alaa Salem M, Almisbahy M.   +12 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Optimal Shrinkage Estimations for the Parameters of Exponential Distribution Based on Record Values

Revista Colombiana de Estadística
This paper studies shrinkage estimation after the preliminary test for the parameters of exponential distribution based on record values. The optimal value of shrinkage coefficients is also obtained based on the minimax regret criterion.
HOJATOLLAH ZAKERZADEH, ALI AKBAR JAFARI, MAHDIEH KARIMI   +2 more
doaj  

Ancestral Sequences Cannot be Accurately Reconstructed via Interpolation in a Variational Autoencoder's Latent Space. [PDF]

Bull Math Biol
Gorstein E, Tang M, Bruzzone H, Solís-Lemus C.   +3 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Estimating Fully Observed Recursive Mixed-Process Models with cmp [PDF]

At the heart of many econometric models is a linear function and a normal error. Examples include the classical small-sample linear regression model and the probit, ordered probit, multinomial probit, Tobit, interval regression, and truncateddistribution
David Roodman
core  

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source