Results 131 to 140 of about 54,912 (316)

LPML and LPMLE3 codes: local polynomial maximum likelihood estimator (semi-infinite and 3 point)

open access: yes, 2012
This package contains the LPML and LPMLE3 codes which has been cleaned up for external use. The codes are an updated version belonging to the publications: Determining groundwater-surface water exchange from temperature-time series: Combining a local ...
Anibas, C. (Christian)   +3 more
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Enhancing the accuracy of modeling highly multicollinear CO2 emission data using a novel generalized Poisson Liu regression method

open access: yesAIP Advances
Count data often exhibit dispersion patterns that the standard Poisson regression model struggles to handle, particularly in cases of overdispersion or underdispersion. The generalized Poisson regression model (GPRM) provides a more flexible alternative,
Ali T. Hammad   +3 more
doaj   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Special ridge-type estimator: Simulation and application to chemical data

open access: yesAIP Advances
This study delves into regularization techniques, such as ridge regression, Liu estimator, and Kibria–Lukman estimator, as alternatives to the maximum likelihood method for addressing multicollinearity in beta regression models.
Rasha A. Farghali   +4 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

EMPIRICAL LIKELIHOOD ESTIMATORS OF THE LINEAR SIMULTANEOUS EQUATIONS MODEL

open access: yes
Information theoretic estimators are specified for a system of linear simultaneous equations, including maximum empirical likelihood, maximum empirical exponential likelihood, and maximum log Euclidean likelihood.
Judge, George G.   +2 more
core  

FIML estimation of a bivariate probit selection rule: an application on firm growth and subsidisation [PDF]

open access: yes
This study applies a full information maximum likelihood (FIML) estimator of the sample selection model with bivariate selection rule for the investigation of the impact of subsidised firm foundation from unemployment on employment growth of the firm ...
Reize, Frank
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Simulated Maximum Likelihood Estimation of the Linear Expenditure System with Binding Non-Negativity Constraints [PDF]

open access: yes
This paper discusses issues on the estimation of consumer demand equations subject to binding non-negative constraints. We propose computationally feasible specifications and a simulated maximum likelihood (SML) method for demand systems. Our study shows
Lung-fei Lee, Chihwa Kao, Mark M. Pitt
core  

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