Results 41 to 50 of about 10,314,714 (175)

Batch‐to‐Batch Optimization of pH Shifts in CHO Bioreactor Operations

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Culture pH is an important operating parameter in CHO cell cultures producing mAb since it directly affects growth and specific productivity. Mathematical models can be used to optimize the magnitude and timing of pH shifts provided that they are robust to model errors.
Ali Ghodba, Zahra Negahban, Anne Richelle, Chris McCready, Valerie Ward, Luis Ricardez‐Sandoval, Hector Budman   +6 more
wiley   +1 more source

Sorghum-based gluten-free bread quality optimization – A mixture design approach

Future Foods
Although sorghum is recognized as a healthy and nutritious crop that can contribute to global food security, it remains underutilized in human nutrition.
Etiene Valéria de Aguiar, Beatriz Gutierrez Costa, Fernanda Garcia dos Santos, Ester M.R. Gonçalves, Valéria Aparecida Vieira Queiroz, Vanessa Dias Capriles   +5 more
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

A stability result for volume ratio

, 2020
For a convex body K in R n , the volume quotient is the ratio of the smallest volume of the circumscribed ellipsoids to the largest volume of the inscribed ellipsoids, raised to power 1/n. It attains its maximum if and only if K is a simplex.
Daniel Hug, Rolf Schneider
core  

Herpes simplex virus type 2: epidemiology and management options in developing countries [PDF]

, 2007
Genital herpes simplex virus type 2 (HSV2) is highly prevalent worldwide and an increasingly important cause of genital ulcer disease (GUD). Continued HSV2 transmission is facilitated by the large number of undiagnosed cases, the frequency of atypical ...
Geretti, AM, Paz-Bailey, G., Ramaswamy, M., Paz-Bailey, G, Hawkes, SJ, Hawkes, S. J., Geretti, A. M., Ramaswamy, M   +7 more
core   +1 more source

Resolving the biome debate: ecological and palaeo‐data concur that the extensive tree‐limited grassy biomes of central and north‐western Madagascar are largely anthropogenic

Biological Reviews, EarlyView.
ABSTRACT For millennia, human activities have transformed ecosystems globally. Determining which landscapes are predominantly anthropogenic is crucial to conservation and habitat restoration. Madagascar, a critically‐threatened biodiversity hotspot, is a prominent example.
Grant S. Joseph, Sean Hixon, Colleen L. Seymour, Laurie R. Godfrey, Miguel Pedrono, Karen E. Samonds, Andrinajoro R. Rakotoarivelo, Brooke E. Crowley   +7 more
wiley   +1 more source

Operations Research‐Based Formalisation and Design of Sustainable Reverse Logistics for E‐Waste Supply Chains

Business Strategy and the Environment, EarlyView.
ABSTRACT This study demonstrates how a profitable, lean, and environmentally responsible e‐waste reverse logistics system can be designed using integrated Operations Research (OR) techniques. Addressing the growing urgency of responsible consumption (UN SDG 12) and the projected rise of the e‐waste sector to USD 137.60 billion by 2029, the research ...
Sheeba Pathak, Hajar Fatorachian
wiley   +1 more source

Upper bound limit analysis of coral reef limestone cavern roof stability incorporating a tension‐shear failure mechanism with tensile‐strength cut‐off

Deep Underground Science and Engineering, EarlyView.
For the roof of coral reef limestone caverns, a novel tension‐shear composite failure mechanism was developed. The most critical tensile crack model was identified using a hybrid optimization algorithm, and the stability of the cavern roof was analyzed accordingly.
Dongsheng Xu, Chenxu Li, Chuantan Hou
wiley   +1 more source

Ultrasound findings associated with neonatal acute liver failure secondary to gestational alloimmune liver disease: A case series

JPGN Reports, EarlyView.
Abstract Objectives Gestational alloimmune liver disease is the leading cause of neonatal acute liver failure, hypothesized to emerge from maternal exposure to an antigen that is expressed on fetal hepatocytes, resulting in maternal‐fetal alloimmune attack and activation of the complement cascade.
Naseem Ravanbakhsh, Ashley M. Upton, Chun‐Sing Huang, Nhu Thao N. Galván, John Goss, Sanjiv Harpavat, Jose A. Hernandez   +6 more
wiley   +1 more source