Results 111 to 120 of about 199,323 (305)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Genetic distance predicts trait differentiation at the subpopulation but not the individual level in eelgrass, Zostera marina. [PDF]

, 2018
Ecological studies often assume that genetically similar individuals will be more similar in phenotypic traits, such that genetic diversity can serve as a proxy for trait diversity.
Corre V., Harvey P. H., Hughes A. R., Koroleff F., Platt T., R Core Team, Williams S. L.   +6 more
core   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

The Maximum Standardized Uptake Value Is More Reliable Than Size Measurement in Early Follow-up to Evaluate Potential Pulmonary Malignancies Following Radiofrequency Ablation [PDF]

, 2013
We retrospectively evaluated the accumulation of fluorodeoxy glucose (FDG) in pulmonary malignancies without local recurrence during 2-year follow-up on positron emission tomography (PET)/computed tomography (CT) after radiofrequency ablation (RFA ...
Alafate, Aierken, Fujiwara, Toshiyoshi, Gobara, Hideo, Hiraki, Takao, Ishii, Hiroaki, Kaji, Mitsumasa, Kanazawa, Susumu, Kato, Katsuya, Miyoshi, Shinichiro, Okumura, Yoshihiro, Sato, Shuhei, Shinya, Takayoshi   +11 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Utility of [18F] Fluoro-Deoxyglucose Positron Emission Tomography/Computed Tomography for Staging and Therapy Response Evaluation in Pediatric Rhabdomyosarcoma: A Case Series and Literature Review

Frontiers in Medicine, 2020
Background: The role of [18F] fluoro-deoxyglucose [[18F] FDG] positron emission tomography (PET)/computed tomography (CT) in pediatric rhabdomyosarcoma (RMS) is not well-established.
Ri Sa, Danyan Liu, Hongguang Zhao, Sen Hou, Qiuyu Lin, Feng Guan   +5 more
doaj   +1 more source

THE HOUNSFIELD UNIT AND MAXIMUM STANDARDIZED UPTAKE VALUE OF SINGLE-PHOTON EMISSION COMPUTED TOMOGRAPHY/COMPUTED TOMOGRAPHY IN TEMPOROMANDIBULAR JOINT OSTEOARTHRITIS PATIENTS [PDF]

, 2023
Yun Su Jeong, Ju‐Young Jung, Yvette Park, J. Kim, Jimi Huh   +4 more
openalex   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Differential diagnostic value of 18F-FDG PET/CT for benign and malignant vertebral compression fractures: comparison with magnetic resonance imaging

Cancer Management and Research, 2018
Xiaojiang He,1,* Long Zhao,1,* Xiuyu Guo,1 Liang Zhao,2 Jing Wu,1 Jingxiong Huang,1 Long Sun,1 Chengrong Xie,3 Haojun Chen1 1Department of Nuclear Medicine and Minnan PET Center, Xiamen Cancer Hospital of the First Affiliated Hospital of Xiamen ...
He X, Zhao L, Guo X, Zhao L, Wu J, Huang J, Sun L, Xie C, Chen H   +8 more
doaj  

Bioavailability in soils [PDF]

, 2011
The consumption of locally-produced vegetables by humans may be an important exposure pathway for soil contaminants in many urban settings and for agricultural land use.
A Göthberg, A Marin, ACC Plette, AJ Maclean, AL Nolan, AL Nolan, B Buchter, BD Traulsen, BE Davies, BJ Alloway, BS Haslett, BS Shane, C Cobbett, CA Grant, CA Grant, CA Grant, CH Williams, CJ Cappon, CL Luo, CN Geng, CS Hassler, CS Hassler, D Sauerbeck, D Voutsa, DE Salt, DE Salt, DJ Brus, DJ Brus, DJ Brus, DJ Hatch, DM Toro Di, DR Parker, E Brand, E Grill, E Sipter, E Smolders, E Smolders, E Smolders, E Sposito, EA Woolson, EE Cary, EJJ Kalis, F Degryse, F Degryse, F Degryse, F Degryse, F Douay, F Haghiri, FJ Zhao, G Jansson, G Sposito, GA Fleming, GM Thomas, GP Warren, GT Yuran, H Mosbaek, HCH Hahne, IM McKenna, IO Plekhanova, J Ingwersen, JA Ericksen, JC Popelka, JC Tjell, JE Eriksson, JL Hall, JL Hopper, JL Wang, JL Xu, JM Gong, JR Preer, JR Preer, JR Wang, JW Dalenberg, JW Dalenberg, KC Jones, KG Tiller, KR Dunbar, LA Sparrow, LD Tyler, LL Hendrickson, LP Weng, LP Weng, M Helal, M Krauss, M Quaghebeur, M Sobotik, MB McBride, MF Hovmand, MI Mattina, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, MJ McLaughlin, ML Adams, MR Farfel, MTF Wong, NA Maier, NA Maier, OK Vatamaniuk, PD Alexander, PFAM Römkens, PJ Florijn, PJ Florijn, PJ Florijn, PJ Florijn, PMC Antunes, PMC Antunes, PR Anderson, Q Xue, R Hough, R Rellan-Alvarez, R Vogeli-Lange, RA Efroymson, RA Khattak, RH Dowdy, RJ Bowell, RJ Reid, RJM Hudson, RL Chaney, RL Chaney, RL Chaney, RL Hough, RL Hough, RM Harrison, RN Collins, RN Reese, RP Narwal, RT Checkai, S Clemens, S Goldberg, S Goldberg, S Sauvé, S Sauvé, S Tandy, S Tandy, S Thakali, SA Barber, SDW Comber, SE Lorenz, SL Brown, SL McGowen, SN Adams, SN Whiting, SP McGrath, T Adhikari, T Cheng, T Kuboi, T Sterckeman, TL Creger, V Page, W Peijnenburg, W Vries de, W Vries de, WJ Garcia, WP Chen, X Cao, X Du, XP Wang, Y Guo, Y Nakamaru, YT Guo   +164 more
core   +2 more sources