Results 161 to 170 of about 12,681,973 (219)

Differential FGFR1 copy number status displays unique tumour immune microenvironment in triple‐negative breast cancer

The Journal of Pathology, EarlyView.
Abstract Fibroblast growth factor receptor 1 (FGFR1) amplification, a significant cancer alteration with both prognostic and therapeutic relevance, lacks a standardized definition. The relationship between FGFR1 copy number (CN) variations and tumour microenvironment (TME) characteristics also remains poorly understood.
Yike Gao, Fei Yao, Junyi Pang, Tianlin Sun, Changbin Zhu, Shafei Wu, Zhiyong Liang   +6 more
wiley   +1 more source

The Spectrum of Kidney Biopsy Findings in Dakota People in the United States. [PDF]

Kidney Int Rep
Abdalla MS, Vaughan LE, Kalantari K, Bu L, Musa TI, Nasr SH.   +5 more
europepmc   +1 more source

Comparative efficacy and safety of tension band wiring versus plate fixation for olecranon fractures: a meta-analysis and trial sequential analysis of randomized clinical trials. [PDF]

JSES Rev Rep Tech
Alshayban MA, Ibraheem AK, Aloudah AA, Alqahtani TS, Elseaidy MN, Abdelmalek M, Mourad MA.   +6 more
europepmc   +1 more source

QSP Modeling Shows Pathological Synergism Between Insulin Resistance and Amyloid‐Beta Exposure in Upregulating VCAM1 Expression at the BBB Endothelium

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 561-571, March 2025.
ABSTRACT Type 2 diabetes mellitus (T2DM), characterized by insulin resistance, is closely associated with Alzheimer's disease (AD). Cerebrovascular dysfunction is manifested in both T2DM and AD, and is often considered as a pathological link between the two diseases.
Zengtao Wang, Vaishnavi Veerareddy, Xiaojiao Tang, Kevin J. Thompson, Sunil Krishnan, Krishna R. Kalari, Karunya K. Kandimalla   +6 more
wiley   +1 more source

Elevated Endogenous Insulin and Insulin Resistance Are Associated With Progressive Diastolic Dysfunction and Worse Cardiovascular Outcomes. [PDF]

Circ Heart Fail
Adel FW, Gochanour B, Scott C, Singh J, Malsawmzuali JC, Ma X, Chen HH.   +6 more
europepmc   +1 more source

Efficacy and Safety of Cannabis Derivates and Their Synthetic Analogs. Overview of Systematic Reviews

Phytotherapy Research, EarlyView.
ABSTRACT The use of medicinal products derived from cannabis and its synthetic analogues has grown in recent years for various health conditions, which led to an increase in systematic reviews (SR) on the topic. The objective of this overview was to identify, synthesize, and critically appraise the evidence from SR on the benefits and harms of cannabis
Rafael Leite Pacheco, Daniela Fortunato Rêgo, Carolina de Oliveira Cruz Latorraca, Marco Aurelio de Carvalho Nascimento, André Bastos Daher, Rachel Riera   +5 more
wiley   +1 more source

Spatially resolved single-cell landscape of tumor immunotypes reveals the central role of interferon signaling and plasmacytoid dendritic cells in triple-negative breast cancer. [PDF]

J Immunother Cancer
Liu Y, Carter JM, Ma Y, Deshmukh SK, Sledge GW, Balko JM, Kachergus JM, Shi J, Gregory M, Gong J, Joensuu H, Perez EA, Stover D, Carey L, Sikov WM, Leon-Ferre R, Knutson KL, Boughey JC, Ingle JN, Kalari KR, Couch FJ, Asmann YW, Goetz MP, Thompson EA, Chumsri S.   +24 more
europepmc   +1 more source

Paradigms and Principles for Integrating Nature Technology Data: Challenges, Opportunities, and Next Steps in Real‐World Biodiversity Monitoring

Remote Sensing in Ecology and Conservation, EarlyView.
We propose a set of paradigms (survey design, tip and cue, validation, consilience, interpolation and extrapolation, and data fusion) and prioritize a set of principles (metadata standards, use rights and licensing, scientific rigor, and utility) as the foundations of an actionable framework for nature technology data integration. We then analyze seven
Seamus Lombardo, Amy Rosenthal, Christopher Anderson, Ken Bagstad, Carly Batist, Christopher Beirne, Paul Bunje, Marconi Campos‐Cerqueira, Jeremy Cusack, Elsa Carla De Grandi, Rachel King, Trond Larsen, David Luther, Jennifer McGowan, Adrien Pajot, Xavier Raick, Vijay Ramesh, Chelsea Smith, Ali Swanson, Tom Walker   +19 more
wiley   +1 more source

Predicting Complications After Radical Nephrectomy With Venous Tumor Thrombectomy and Various IVC Reconstruction Approaches: A Simplified Risk Calculator. [PDF]

Urology
Roberson DS, Basourakos SP, Dorr M, Joyce DD, Henning GM, McLeay MT, Khanna A, Thiels CA, Shuja F, DeMartino RR, Cheville JC, Boorjian SA, Leibovich BC, Sharma V.   +13 more
europepmc   +1 more source

Exploring Drivers and Mitigation Strategies for Food Manufacturing Wastes in the Circular Economy Using Rich Pictures

Sustainable Development, EarlyView.
ABSTRACT This study aims to identify the main types, drivers, and solutions for food loss and waste (FLW) as reported by stakeholders within the UK food manufacturing sector from a Circular Economy perspective. Based on insights from diagramming‐based workshops involving 35 participants working in an organisation in the sector, FLW occurs primarily as ...
Alexander Moores, Dimitris Charalampopoulos, Adrian Williams, Ximena Schmidt Rivera   +3 more
wiley   +1 more source