Results 41 to 50 of about 12,681,973 (219)

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel   +6 more
wiley   +1 more source

Rheumatoid arthritis, frailty, and outcomes of surgical hospitalizations: A national population‐based analysis

open access: yesArthritis Care &Research, Accepted Article.
OBJECTIVE Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective non‐cardiac surgery. METHODS We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including ...
Ali Yazdanyar   +5 more
wiley   +1 more source

Apolipoprotein C-II Deposition Amyloidosis: A Potential Misdiagnosis as Light Chain Amyloidosis

open access: yesCase Reports in Nephrology, 2016
Hereditary amyloidoses are rare and pose a diagnostic challenge. We report a case of hereditary amyloidosis associated with apolipoprotein C-II deposition in a 61-year-old female presenting with renal failure and nephrotic syndrome misdiagnosed as light ...
Sadichhya Lohani   +4 more
doaj   +1 more source

Nonalcoholic steatohepatitis and intestinal microflora: the question of potential of prebiotic medicines

open access: yesМедицинский совет, 2013
More than 30 years ago, Jurgen Ludwig et al. from Mayo Clinic (USA, Minnesota) for the first time at biopsy described typical signs of parenchyma lesions in alcoholic liver disease in patients who did not consume hepatotoxic doses of alcohol but were ...
Yu. A. Kucheryaviy   +3 more
doaj   +1 more source

Human‐Scale Rotating Magnetic Field Delivery With Permanent Magnets Under Anatomic and Robotic Constraints

open access: yesAdvanced Robotics Research, EarlyView.
Rotating magnetic fields (RMFs) are widely used for microrobot propulsion and control. We show that RMF generation with permanent magnets is mechanically feasible for many limb and intracranial applications but becomes constrained for thoracic targets.
Tuan‐Anh Le   +4 more
wiley   +1 more source

Analysis of surgical treatment outcomes for renal cell carcinoma with inferior vena cava tumor thrombosis: a single-center experience

open access: yesСибирский онкологический журнал
The purpose of the study was to analyze surgical treatment outcomes for renal cell carcinoma (RCC) with inferior vena cava tumor thrombosis (IVC-TT) on the basis of one cancer center.Material and Methods. A retrospective analysis of treatment outcomes of
S. V. Gamayunov   +6 more
doaj   +1 more source

Integrative Multi‐Omics Analysis Reveals a Mitochondrial–Immune Axis Associated With Neoadjuvant Chemotherapy Response in High‐Grade Serous Ovarian Cancer

open access: yesAdvanced Science, EarlyView.
Integrative multi‐omics analysis delineates a mitochondrial–immune axis governing neoadjuvant chemotherapy response in high‐grade serous ovarian cancer. Immune‐active tumors exhibit enhanced B‐cell infiltration and favorable sensitivity, whereas metabolically rewired tumors display oxidative phosphorylation dependency and resistance.
Wei Jiang   +11 more
wiley   +1 more source

Kapanji Technique in Pediatric Head and Neck Radius Fractures [PDF]

open access: yesAl-Azhar International Medical Journal
Background: Most pediatric head and neck fractures are type I and type II, which contain the radius bone and are undisplaced or minimally displaced. Closed reduction and cast immobilization can treat these fractures successfully.Aim and objectives: To ...
Ibrahim Hussein   +2 more
doaj   +2 more sources

Minimally Invasive Treatment of Mason Type II Radial Head Fracture by Intramedullary Pinning

open access: yesOrthopaedic Surgery, 2019
Objective To evaluate the outcome of Mason type II radial head fractures treated by intramedullary pinning. Methods From May 2013 to March 2017, we respectively reviewed 25 patients affected by Mason type II radial head fractures.
Xu Gao, Hai‐lei Yin, Guang‐jie Zhou
doaj   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

open access: yesAdvanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye   +9 more
wiley   +1 more source

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