Results 41 to 50 of about 7,327 (168)

Pollution and Haunted Eco‐Histories: Silent Hill and Silent Horrors in Centralia, Pennsylvania

Popular Culture Review, Volume 37, Issue 2, December 2026.
ABSTRACT Centralia is a former mining town and borough in Northeastern Pennsylvania, whose population has been steadily declining since the Mine Fire of 1962—a fire that still burns today. The “horrors” of living in Centralia are reflected in horror media set in postindustrial mining towns like Silent Hill.
Maz Jardon
wiley   +1 more source

The role of serial blood tests during expectant management of early preeclampsia with severe features

Pregnancy, Volume 2, Issue 5, September 2026.
Abstract Background Expectant management of early‐onset preeclampsia with severe features (<34 weeks’ gestation) requires close maternal surveillance. Although serial testing is routinely performed, recommendations regarding testing frequency vary across professional societies and the clinical utility and financial impact of frequent testing during ...
Zakaria Doughan, Yossi Bart, Joe Haydamous, Laura Diab, Sara Giuliano, Ahmed Zaki Moustafa, Farah H. Amro, Baha M. Sibai   +7 more
wiley   +1 more source

MACROECONOMIC FACTORS AS TOOLS FOR STIMULATION OR DESTIMULATION OF AGRIBUSINESS LOANS IN CRISIS SITUATION

Polityki Europejskie, Finanse i Marketing, 2022
The study attempts to identify changes in the loan market for agribusiness enterprises, including farms in Poland, during the COVID-19 pandemic. The research used data from the Central Statistical Office and the Credit Information Bureau for 2017-2020 ...
Sławomir Juszczyk, Wioleta Bartosiak, Bartosz Kublik, Łukasz Mleczko   +3 more
doaj   +1 more source

Ultrasound, PET/CT or temporal artery biopsy for giant cell arteritis? A prospective diagnostic accuracy study (the GAME‐study)

Acta Ophthalmologica, Volume 104, Issue 6, Page e695-e708, September 2026.
Abstract Purpose To investigate the diagnostic performance of ultrasound, 2‐deoxy‐2‐[18F]fluoro‐D‐glucose positron emission tomography/computed tomography (2‐[18F]FDG PET/CT) and temporal artery biopsy (TAB) in giant cell arteritis (GCA). Methods This was a prospective single‐centre diagnostic accuracy study (ClinicalTrials.gov NCT05248906).
Michael S. Hansen, Lene Terslev, Uffe M. Døhn, Viktoria Fana, Jane M. Brittain, Anne K. Wiencke, Steffen Heegaard, Mads R. Jensen, Oliver N. Klefter, Yousif Subhi, Steffen Hamann   +10 more
wiley   +1 more source

G-quadruplexes promote the motility in MAZ phase-separated condensates to activate CCND1 expression and contribute to hepatocarcinogenesis

Nature Communications
G-quadruplexes (G4s) can recruit transcription factors to activate gene expression, but detailed mechanisms remain enigmatic. Here, we demonstrate that G4s in the CCND1 promoter propel the motility in MAZ phase-separated condensates and subsequently ...
Wenmeng Wang, Dangdang Li, Qingqing Xu, Jiahui Cheng, Zhiwei Yu, Guangyue Li, Shiyao Qiao, Jiasong Pan, Hao Wang, Jinming Shi, Tongsen Zheng, Guangchao Sui   +11 more
doaj   +1 more source

23S rRNA as an a-Maz-ing new bacterial toxin target [PDF]

RNA Biology, 2014
Mycobacterium tuberculosis, the causative agent of tuberculosis in humans, is a bacterium with the unique ability to persist for years or decades as a latent infection. This latent state, during which bacteria have a markedly altered physiology and are thought to be dormant, is crucial for the bacteria to survive the stressful environments it ...
Jason M, Schifano, Nancy A, Woychik
openaire   +2 more sources

Molecular mechanisms of MAZ targeting up-regulation of NDUFS3 expression to promote malignant progression in melanoma

Communications Biology
Myc-associated Zinc-finger Protein (MAZ) has been implicated in the malignant progression of various tumors. However, its expression and functional relationship of MAZ in melanoma have not been previously investigated.
Yu Feng, Qinxuan Ni, Na Wu, Taiyu Xie, Fang Yun, Xuedan Zhang, Lingnan Gao, Yanlong Gai, Enjiang Li, Xiaojia Yi, Junlin Xie, Qiao Zhang, Zhe Yang, Buqing Sai, Yingmin Kuang, Yuechun Zhu   +15 more
doaj   +1 more source

Long‐Acting Cabotegravir/Rilpivirine Reduces Immune‐Activation and ‐Senescence in People With HIV With CMV Co‐Infection

Immunology, Volume 179, Issue 1, Page 138-148, September 2026.
This study investigates the impact of switching to long‐acting (LA) injectable cabotegravir and rilpivirine (CAB/RPV‐LA) on immune‐activation and ‐senescence in people with HIV (PWH). Thirty‐seven PWH switching to CAB/RPV‐LA and nine continuing oral ART were analysed over 72 weeks. LA therapy led to significant reductions in activation T and senescence
Mariasilvia Guardiani, Eeva Tortellini, Anna Carraro, Maria Antonella Zingaropoli, Lorenzo Ansaldo, Alessandra Grimaldi, Serena Vita, Federica Dominelli, Fabio Mengoni, Caterina Pasquazzi, Ombretta Turriziani, Maria Rosa Ciardi, Vincenzo Vullo, Claudio Maria Mastroianni, Raffaella Marocco, Cosmo Del Borgo, Miriam Lichtner   +16 more
wiley   +1 more source

Identification of Epigenetic Regulator‐Associated Genes in Keloid Disease Through Integrated Bulk and Single‐Cell Transcriptomics With RT‐qPCR Validation

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
Step I: Screened HR/SMYD4 as key keloid epigenetic genes via bulk/scRNA‐seq and machine learning. Step II: Built a high‐performance nomogram (AUC = 0.988). Step III: Conducted multi‐omics analyses. Step IV: Experimentally verified their differential expression and pathogenic roles.
Yifei Wang, Shuqian Dou, Mingkun Dai, Guoxun Yang, Wenjun Liu   +4 more
wiley   +1 more source

G‐Quadruplexes: Structural Diversity and Emerging Roles in Biomolecular Condensation

Advanced Science, Volume 13, Issue 45, 13 August 2026.
G‐quadruplexes (G4s) fold into diverse intra‐ and intermolecular structures, positioning them as emerging regulators of biomolecular condensation. Mechanistically, G4s autonomously form condensates, act as structural platforms to initiate and stimulate condensation, or induce phase transitions.
Wenmeng Wang, Qingqing Xu, Yuxin Zhang, Fang Liu, Guangchao Sui, Dangdang Li   +5 more
wiley   +1 more source