Results 161 to 170 of about 241,616 (251)

Animal stroke models and outcome evaluation: A review

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba   +2 more
wiley   +1 more source

Genetic Resilience and Resistance in Alzheimer's Disease Diagnosis and Pathology

open access: yesAnnals of Neurology, EarlyView.
Objective Some individuals avoid Alzheimer's disease (AD) pathology as they age, or retain cognition despite substantial pathology, suggesting mechanisms of resistance or resilience to neurodegeneration. Educational attainment (EA) is associated with reduced risk of cognitive decline, although the underlying mechanisms remain unclear.
Ganna Leonenko   +8 more
wiley   +1 more source

Functional Polymer‐Engineered Magnetic Nanoparticles as Dual‐Modal Theragnostic Probes for Early Alzheimer's Disease Detection and Therapy

open access: yesAdvanced NanoBiomed Research, EarlyView.
The nanoparticle consists of a 3 nm iron oxide core functionalized with an amphiphilic polymer coating containing Aβ‐targeting DSA moieties and biocompatible PEG chains. This design supports measurable transport in a BBB‐related model and specific interaction with Aβ species, while providing MRI contrast enhancement for diagnosis and therapeutic ...
Ao Shen   +8 more
wiley   +1 more source

Manic switching from depression is affected by adult hippocampal neurogenesis. [PDF]

open access: yesAnim Cells Syst (Seoul)
Song J   +9 more
europepmc   +1 more source

Design and Performance of a High‐Efficiency Inhibitor: Synergistic Effect of Modified Chitosan and Boron Nitride Nanosheets on Steel Protection

open access: yesAsia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Metal corrosion causes significant economic losses and safety hazards, underscoring the urgent need for effective, environmentally friendly corrosion inhibitors. In this study, an organic–inorganic composite inhibitor, chitosan–glucose–BN (CS–GL–BN) was developed to protect Q235 mild steel in a 3.5‐wt% NaCl solution.
Shanjun Xu   +4 more
wiley   +1 more source

Are there morpho‐acoustic patterns of adaptation in nonhuman primate ears? Testing the role of ecology and habitat in shaping ear morphology and function

open access: yesThe Anatomical Record, EarlyView.
Abstract Analysis of the variation in the bony structures of the inner and middle ear provides critical insights into functional morphology, as well as adaptive morphology across primates. In this study, we investigated whether ear morphology patterns are related to the ecological characteristics of species and their habitats to test two acoustic ...
Myriam Marsot   +4 more
wiley   +1 more source

Beyond the Maze: Hybrid Ablation and Left Atrial Appendage Occlusion in Cardiac Surgery: Evidence Synthesis and the MESAGE Study Protocol. [PDF]

open access: yesMedicina (Kaunas)
Kotoulas SC   +8 more
europepmc   +1 more source

Statistical shape modeling of the human inner ear through micro‐computed tomography imaging

open access: yesThe Anatomical Record, EarlyView.
In this study, 54 cadaveric temporal bone specimens underwent high‐resolution micro‐CT imaging. Images were semi‐automatically segmented and converted to 3D surface mesh models for morphological measurement and analysis. Statistical shape models were created for the inner ear, cochlea, and vestibular system, as well as for sex‐ and side‐based subgroups.
Carmine Spedaliere   +8 more
wiley   +1 more source

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