Results 31 to 40 of about 241,616 (251)

Effects of methimepip and JNJ-5207852 in Wistar rats exposed to an open-field with and without object and in Balb/c mice exposed to a radial-arm maze [PDF]

, 2012
The role of the histamine H3 receptor (H3R) in anxiety is controversial, due to limitations in drug selectivity and limited validity of behavioral tests used in previous studies. In the present report, we describe two experiments.
Paul L. Chazot, Lethbridge, Natasha L., Ruan van Rensburg, Chazot, Paul L., Rushdie M. A. Abuhamdah, Abdel Ennaceur, Abuhamdah, Rushdie M., Natasha L. Lethbridge, van Rensburg, Ruan, Ennaceur, Abdelkader   +9 more
core   +1 more source

Trends in surgical ablation at the time of cardiac surgery among patients with atrial fibrillationCentral MessagePerspective

JTCVS Open, 2023
Background: The 2017 American Association for Thoracic Surgery (AATS) guidelines support surgical ablation in patients undergoing cardiac surgery with preoperative atrial fibrillation (AF) owing to a reduction in early mortality and improved overall ...
Haley N. Jenkins, MD, Aaron J. Weiss, MD, PhD, Jean-Luc A. Maigrot, BS, Guangjin Zhou, PhD, Siran M. Koroukian, PhD, A. Marc Gillinov, MD, Lars Svensson, MD, PhD, Edward G. Soltesz, MD, MPH   +7 more
doaj   +1 more source

Superiority of cut-and-sew technique for the Cox maze procedure: Comparison with radiofrequency ablation [PDF]

, 2007
ObjectiveAlthough radiofrequency ablation is increasingly used to create the atrial lesions of the Cox maze procedure, its effectiveness in ablating atrial fibrillation compared with the standard cut-and-sew method is not known.
Zehr, Kenton J., Schaff, Hartzell V., Sundt, Thoralf M., Dearani, Joseph A., McGregor, Christopher G.A., Stulak, John M., Daly, Richard C.   +6 more
core   +1 more source

Behavioural phenotyping, learning and memory in young and aged growth hormone-releasing hormone-knockout mice

Endocrine Connections, 2018
Background: Growth hormone-releasing hormone (GHRH) plays an important role in brain functions. The aim of this study was to examine cognitive functions and emotional behaviour in a mouse model of isolated GH deficiency due to bi-allelic ablation of the ...
Sheila Leone, Lucia Recinella, Annalisa Chiavaroli, Claudio Ferrante, Giustino Orlando, Michele Vacca, Roberto Salvatori, Luigi Brunetti   +7 more
doaj   +1 more source

Postoperative metabolic acidosis following the minimally invasive radiofrequency maze procedure

Annals of Cardiac Anaesthesia, 2016
Purpose: Atrial fibrillation (AF) is the most common arrhythmia treated in the world. While medical treatment with antiarrhythmic drugs remains the primary treatment modality, symptomatic refractory AF often requires treatment with a catheter or surgical
Raymond Patrick Hom, Anna Dubovoy, Elizabeth Jewell, Milo Engoren   +3 more
doaj   +1 more source

Electrical conductivity measurement in Thiel-embalmed tissue model : relevance to radiofrequency ablation [PDF]

, 2014
PA gratefully acknowledges SUPA for funding his Advanced Research Fellowship.Thiel-embalmed human cadaveric specimens are used widely for biomedical scientific investigation.
Andre, P., Luo, Hongyan, Luo, H., Baker, R. T., Brown, S., Gueorguieva, M., Wang, Zhigang, Nick, M., Cuschieri, A., Wang, Z., Baker, R.T., McLean, D.   +11 more
core   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Tau reduction diminishes spatial learning and memory deficits after mild repetitive traumatic brain injury in mice. [PDF]

PLoS ONE, 2014
Because reduction of the microtubule-associated protein Tau has beneficial effects in mouse models of Alzheimer's disease and epilepsy, we wanted to determine whether this strategy can also improve the outcome of mild traumatic brain injury (TBI).We ...
Jason S Cheng, Ryan Craft, Gui-Qiu Yu, Kaitlyn Ho, Xin Wang, Geetha Mohan, Sergey Mangnitsky, Ravikumar Ponnusamy, Lennart Mucke   +8 more
doaj   +1 more source

The Design and Implementation of Multi-Maze

, 2017
Maze puzzle usually has only one user. This research has adopted network technology to develop a maze game, called Multi-Maze, which allows multiple players competing across the network concurrently. It contains three sub-systems.
Liaw, Heh-Tyan; Jou, Chichang; Liou, Ay-Hwa Andy; Debnath, Narayan C.
core   +1 more source