Results 81 to 90 of about 241,616 (251)

EphB1‐Mediated Transient Blood‐Brain Barrier Opening Facilitates a Ferritin‐Based Nanotherapeutic for Alzheimer's Disease

Advanced Science, EarlyView.
We constructed a brain‐targeted AFn‐DPZ nanodrug delivery system and identified EphB1 as its receptor on the blood‐brain barrier (BBB). This system facilitates drug transport across the BBB and thereby ameliorates cognitive impairment in Alzheimer's disease.
Shilin Wen, Jingjing Gao, Zhixian Wang, Qiumin Ma, Xiao‐Ling Xu, Jianer Chen   +5 more
wiley   +1 more source

Minimally invasive surgical treatment of atrial fibrillation: Initial experience with the Wolf Mini Maze

Cardiologia Hungarica
There are several minimally invasive surgical techniques available in the interventional therapy of atrial fibrillation (AF) besides catheter ablation.
Marcell Székely, János Tomcsányi, Péter Arányi, Dániel Lex, László Székely   +4 more
doaj   +1 more source

Robot Path Planning for Maze Navigation

, 1998
This paper presents the application of multilayer perceptrons to the robot path planning problem, and in particular to the task of maze navigation. Previous published results implied that the training of feedforward multilayered networks failed, because ...
Dracopoulos, D.
core   +1 more source

Data_Sheet_1_Catheter ablation and thoracoscopic ablation in long persistent atrial fibrillation with large left atrium.docx

, 2022
BackgroundPulmonary vein antrum isolation (PVAI) is the cornerstone of atrial fibrillation (AF) ablation, but the clinical outcomes of PVAI are unsatisfactory in patients with persistent AF and a large left atrium (LA).ObjectivesWe investigated the ...
Eue-Keun Choi (3536411), Soonil Kwon (198024), Sunhwa Kim (4491526), Ho Young Hwang (4252084), Jae Woong Choi (1403143), Seil Oh (4707793), So-Ryoung Lee (4707796), Hyo-Jeong Ahn (10007721), Suk Ho Sohn (12872365), Chan Soon Park (3875374)   +9 more
core   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

Advanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang, Juan Yang, Xin Jiang, Zhanghui Zheng, Hongyu Wei, Na Li, Xiangqiang Chu, Weizhi Liu   +7 more
wiley   +1 more source

Is ganglionated plexi ablation during Maze IV procedure beneficial for postoperative long-term stable sinus rhythm?

, 2015
Background: We investigated the role of surgical ablation targeting the autonomous nervous system during a Cox-Maze IV procedure in the maintenance of sinus rhythm at long-term follow-up.
Gelsomino, Sandro, Renzulli, Attilio, Luca, Fabiana, Rostagno, Carlo, La Meir, Mark, Lozekoot, Pieter, Lorusso, Roberto, Crjins, Harry J. G. M., Parise, Orlando, Gensini, Gian Franco, Maessen, Jos G., Maessen, Jos G.; id_orcid, Matteucci, Francesco   +12 more
core   +1 more source

Neuron‐Targeted Exosomal Delivery of siRNA Against RIPK3 Slows Neurodegenerative Progression in Alzheimer's Disease

Advanced Science, EarlyView.
Engineered exosomal siRNA delivery platform enables systemic, neuron‐targeted RNA transport across the blood–brain barrier. Surface functionalization with rabies virus glycoprotein‐derived peptide facilitates receptor‐mediated transcytosis, achieving efficient cytosolic delivery and robust gene silencing. Targeting RIPK3 suppresses necroptosis, reduces
Chi Zhang, Jiaqi Zhang, Yuzhi Wang, Yaodong Wang, Peng Lin, Yanling Wang, Zixuan Tang, Jintai Yu, Qin Zhou, Feiyun Cui   +9 more
wiley   +1 more source

Thoracoscopic Ex-Maze III procedure and radiofrequency catheter ablation - a hybrid therapy for permanent atrial fibrillation : a case report [PDF]

, 2009
We desribe a case of a 57-year-old patient with persistent longstanding atrial fibrillation (AF) in whom paracardioscopic Ex-Maze III procedure converted AF to typical counterclockwise atrial flutter.
Myć, Jacek, Bartuś, Krzysztof, Majewski, Jacek, Sadowski, Jerzy, Lelakowski, Jacek, Kapelak, Bogusław   +5 more
core  

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Maze, Randall A.: my naval experiences (November 22, 2006)

, 2006
Interviewer: Perry, MarieInterviewee: Maze, Randall A.Rank: Commander.ABSTRACT: Commander Randall Maze Commander Maze Interview.mp3 (0:00) Received university education through Regular Training Program, UVIC. His father was in the navy.

core   +1 more source