Results 101 to 110 of about 108,579 (365)

A Trypsin‐Like Serine Protease ZmNAL1a Fine‐Tunes Maize Floral Transition and Flowering Time

open access: yesAdvanced Science, EarlyView.
This study identifies a trypsin‐like serine protease, ZmNAL1a, that moves from leaves to the shoot apical meristem. ZmNAL1a promotes the floral transition by degrading TOPLESS‐like corepressor REL2, which thereby enhances the expression of key flowering genes through elevating histone acetylation and relieving REL2–ZmEREBP147‐mediated transcriptional ...
Nan Li   +15 more
wiley   +1 more source

Caenorhabditis elegans Muscleblind homolog mbl-1 functions in neurons to regulate synapse formation

open access: yesNeural Development, 2012
BackgroundThe sequestration of Muscleblind splicing regulators results in myotonic dystrophy. Previous work on Muscleblind has largely focused on its roles in muscle development and maintenance due to the skeletal and cardiac muscle degeneration ...
Kerri A. Spilker   +3 more
semanticscholar   +1 more source

Sensitive CSF ELISAs for the detection of MBL, MASP-2 and functional MBL/MASP-2 [PDF]

open access: yesJournal of Neuroscience Methods, 2012
Mannose binding lectin (MBL) mediated complement pathway is an important constituent of innate immune response in several infections including neuroinflammatory and neurodegenerative diseases. Although there are Enzyme-Linked Immunosorbent Assays (ELISAs) for estimating MBL, MBL-associated serine protease-2 (MASP-2) and functional MBL-MASP-2 (fMBL ...
Janet Y, Kwok   +3 more
openaire   +2 more sources

Evolution of Multivalent Aptamer Corona for High‐Throughput Multiplexed Detection of Multiple Cancers

open access: yesAdvanced Science, EarlyView.
A multivalent aptamer corona is evolved via established ProteoFish‐SELEX (systematic evolution of ligands by exponential enrichment) for high‐throughput multiplexed detection of multiple cancers. Clinical validation using multivalent aptamer corona demonstrated high accuracy and specificity in multiplexed detection of ovarian, lung, and colorectal ...
Mengjie Wang   +10 more
wiley   +1 more source

Thermal inclusions: how one spin can destroy a many-body localized phase

open access: yes, 2017
Many-body localized (MBL) systems lie outside the framework of statistical mechanics, as they fail to equilibrate under their own quantum dynamics. Even basic features of MBL systems such as their stability to thermal inclusions and the nature of the ...
Chandran, A.   +3 more
core   +1 more source

MBL-Mediated Opsonophagocytosis of Candida albicans by Human Neutrophils Is Coupled with Intracellular Dectin-1-Triggered ROS Production

open access: yesPLoS ONE, 2012
Mannan-binding lectin (MBL), a lectin homologous to C1q, greatly facilitates C3/C4-mediated opsonophagocytosis of Candida albicans (C. albicans) by human neutrophils, and has the capacity to bind to CR1 (CD35) expressed on circulating neutrophils.
Dongsheng Li   +10 more
semanticscholar   +1 more source

Interaction of C1q and Mannan-Binding Lectin (MBL) with C1r, C1s, MBL-Associated Serine Proteases 1 and 2, and the MBL-Associated Protein MAp19 [PDF]

open access: yesThe Journal of Immunology, 2000
Abstract Mannan-binding lectin (MBL) and C1q activate the complement cascade via attached serine proteases. The proteases C1r and C1s were initially discovered in a complex with C1q, whereas the MBL-associated serine proteases 1 and 2 (MASP-1 and -2) were discovered in a complex with MBL.
Thiel, S   +7 more
openaire   +4 more sources

GbWAKL20 Phosphorylates GbNFYB8 to Modulate Verticillium Wilt Resistance in Cotton

open access: yesAdvanced Science, EarlyView.
Wall‐associated receptor‐like kinases (WAKLs) play pivotal roles in extracellular–intracellular signal transduction. Upon sensing Verticillium dahliae infestation at the plasma membrane, GbWAKL20 accumulates and transmits signals to the nucleus via endoplasmic reticulum‐mediated Golgi vesicle transport.
Guilin Wang   +7 more
wiley   +1 more source

As bases da nova direita: estudo de caso do Movimento Brasil Livre na cidade de São Paulo (2013-2016)

open access: yesConversas & Controvérsias, 2018
O presente artigo é o resultado de pesquisas bibliográficas e de observação de campo realizada durante as manifestações em favor do impedimento de Dilma Rousseff.
Ederson Duda da Silva
doaj   +1 more source

Kosterlitz-Thouless scaling at many-body localization phase transitions

open access: yes, 2019
We propose a scaling theory for the many-body localization (MBL) phase transition in one dimension, building on the idea that it proceeds via a 'quantum avalanche'.
Dumitrescu, Philipp T.   +4 more
core   +1 more source

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