Results 281 to 290 of about 108,579 (365)

Activity of novel antibiotics against dual metallo-Beta-lactamase producing <i>Enterobacter hormaechei</i> clinical isolates. [PDF]

open access: yesJAC Antimicrob Resist
Solar C   +10 more
europepmc   +1 more source

Foxg1 Defines Ventrolateral Zonal Identity by Sustaining Neurogenic Progenitor Potential in the Olfactory Epithelium

open access: yesGenes to Cells, Volume 31, Issue 2, March 2026.
Foxg1 maintains neurogenic progenitor potential in the ventrolateral olfactory epithelium. In control (Foxg1‐cHET) embryos, Foxg1‐expressing progenitors preferentially generate olfactory sensory neurons (OSNs) and support V‐zone expansion. Conditional Foxg1 deletion (Foxg1‐cKO) reduces V‐zone growth and shifts progenitor fate toward sustentacular cells
Anzu Kuriyama   +2 more
wiley   +1 more source

Impacts of Transport Uncertainty on CO2 Over North America: Insights From Assessments of Two Global Models With Aircraft and Tower Measurements

open access: yesJournal of Geophysical Research: Atmospheres, Volume 131, Issue 3, 16 February 2026.
Abstract Accurate representation of CO2 transport is important for reliable flux inversions with global inversion systems. Previous studies have revealed systematic discrepancies between two widely used global transport models, GEOS‐Chem and TM5, in simulated CO2 distributions at mid‐latitudes.
Li Zhang   +3 more
wiley   +1 more source

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen   +16 more
wiley   +1 more source

Complement Activation as a Predictor of Postoperative Delirium in Elderly Spine Surgery Patients. [PDF]

open access: yesInt J Mol Sci
Vogelgesang A   +10 more
europepmc   +1 more source

Brd4 BD1 Domain Antagonism of MS436 Preserves Blood‐Brain Barrier Integrity via Rnf43/β‐Catenin Signaling Pathway

open access: yesAdvanced Science, Volume 13, Issue 7, 3 February 2026.
MS436 competitively binds to the BD1 domain of Brd4, thereby suppressing Brd4 induced degradation of tight junction proteins via the Rnf43‐Fzd4‐β‐catenin signaling pathway. Consequently, this attenuation of degradation reduces blood‐brain barrier leakage, leading to an improved overall prognosis after stroke.
Chenxiao Li   +10 more
wiley   +1 more source

Temporal dynamics of white matter hyperintensities related to Alzheimer's disease in adults with Down syndrome

open access: yesAlzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION White matter hyperintensities (WMH) are common in Down syndrome (DS), yet their longitudinal evolution and associations with Alzheimer's disease (AD) remain unclear. METHODS Longitudinal MRI study, including 80 DS adults and 53 euploid controls. WMH were segmented on serial FLAIR using a longitudinal pipeline.
Alejandra O. Morcillo‐Nieto   +24 more
wiley   +1 more source

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