Results 221 to 230 of about 2,088,465 (288)

Synthesis of USP Grade [2,3,7‐13C3]‐Nicotinamide for Human Pharmacokinetic Studies

Journal of Labelled Compounds and Radiopharmaceuticals, Volume 69, Issue 12, October 2026.
We prepared a 17.8‐g quantity of [2,3,7‐13C3]‐nicotinamide in five synthetic steps, with a 42% overall yield, and purified it to > 99% homogeneity, meeting USP standards for oral pharmaceutical dosing. This material is intended for tracking the movement and metabolism of nicotinamide through the human body.
Bruce G. Szczepankiewicz, Karsten J. Koppetsch, Michael P. Drolet, David Cao, Jonathan N. Kremsky, Eric E. Buck, George Rotsides, Greg Griffin, Siead Zegar, Alan Henderson, David J. Livingston   +10 more
wiley   +1 more source

Measurement of ²²⁷Ac by Isotopic Ratio with ²²⁵Ac Using ICP-MS. [PDF]

ACS Omega
Baumeister JE, Puffer BW, Hawkins CA, McCormick JB, Toro-González M, Brown JW, De Vries DJ.   +6 more
europepmc   +1 more source

Machine Learning‐Based Development of Gadolinium Binding Peptides

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
In this study, Dayan et al. employed a machine‐learning‐driven peptide‐evolution platform, the Protein Optimization Engineering Tool (POET), to design and optimize short Gd‐binding motifs to enhance longitudinal relaxivity (r1). ABSTRACT Gadolinium‐based contrast agents (GBCAs) are indispensable tools in magnetic resonance imaging (MRI), yet their ...
Nir A. Dayan, Makayla Long, Nicolas Scalzitti, Iliya Miralavy, Daniel Holmes, Mark Kocherovsky, Wolfgang Banzhaf, Assaf A. Gilad   +7 more
wiley   +1 more source

A Barcoding Strategy for Pooled Single-Cell LA-ICP-TOFMS Analysis of Metal-Containing Therapeutics. [PDF]

Anal Chem
Molitor C, Hendriks L, Hafner A, Keppler B, Berger W, Koellensperger G.   +5 more
europepmc   +1 more source

Two distinct alcohol dehydrogenase classes mediate bacterial 2‐hydroxyethylphosphonate catabolism

Protein Science, Volume 35, Issue 10, October 2026.
Abstract Phosphonates are molecules containing a direct carbon‐phosphorus bond. In nature, these compounds are produced by a variety of organisms, and many environmental microbes are able to degrade specific phosphonates and feed on them. This work focuses on 2‐hydroxyethylphosphonate (HEP)—a natural compound that is found frequently in the environment,
Francesca Piazza, Marianna Rodella, Nicholas Salanti, Giovanni Merici, Elisa Rossi, Claudio Rivetti, Florian Götzinger, Katharina Pallitsch, Alessio Peracchi   +8 more
wiley   +1 more source

Zinc tolerance through glutathione import strikes a fine balance between protection and damage in <i>Streptococcus mutans</i>. [PDF]

Microbiology (Reading)
Carter MC, Womack E, Khatib M, Peterson AM, Saengpet IS, Lemos JA.   +5 more
europepmc   +1 more source

Impact of Positively Charged Backbone Modifications on the Properties of Spherical Nucleic Acids

Small, Volume 22, Issue 55, 1 October 2026.
A synthesis of spherical nucleic acids (SNAs) featuring cationic backbone modifications is presented, together with an analysis of their emerging properties. Introducing positively charged guanidinium groups near the SNA surface enhances cellular uptake and offers a pathway toward more precise control over SNA internalization.
Katherine E. Bujold, Kacper Skakuj, John P. Cavaliere, Caroline D. Kusmierz, Chad A. Mirkin   +4 more
wiley   +1 more source

Newly Identified Early Cretaceous High-Mg Diorites in the Southern Dayaoshan Area of South China: Petrogenesis and Geodynamic Implications. [PDF]

ACS Omega
Wei Y, Meng L, Zhang Y.
europepmc   +1 more source

Organic and Inorganic Pollutants, Oxidative Stress Biomarkers, and Electrophoretic Protein Profiles in an Endangered Thresher Shark (Alopias vulpinus) From Southeastern Brazil: A Case Study

Environmental Toxicology, Volume 41, Issue 10, Page 833-848, October 2026.
ABSTRACT A comprehensive screening of different environmental contaminants (total metals, thermostable metal fractions associated with detoxification, and persistent organic pollutants) was conducted in an endangered common thresher shark (Alopias vulpinus ) individual incidentally captured in southeastern Brazil.
Sidney Fernandes Sales Junior, Amanda Pontes Lopes, Heloíse Martins de Souza, Regina Fonseca, Enrico Mendes Saggioro, Francielli Monteiro Casanova, Kamila Cezar Gramlich, Tatiana Dillenburg Saint'Pierre, Carlos German Massone, Renato Carreira, Rachel Ann Hauser‐Davis   +10 more
wiley   +1 more source

Human Health Effects of Chronic Microcystin Exposure: A Systematic Review and Meta-Analysis of Hepatic, Renal, and Metabolic Outcomes. [PDF]

Toxins (Basel)
Moon SD, Hwang DS, Lee JS, Hwang SO, Paerl HW, Kim BH.   +5 more
europepmc   +1 more source