Results 11 to 20 of about 163,884 (332)

Interactions of the human MCM-BP protein with MCM complex components and Dbf4. [PDF]

PLoS ONE, 2012
MCM-BP was discovered as a protein that co-purified from human cells with MCM proteins 3 through 7; results which were recapitulated in frogs, yeast and plants.
Tin Nguyen, Madhav Jagannathan, Kathy Shire, Lori Frappier   +3 more
doaj   +1 more source

The dynamics of replication licensing in live Caenorhabditis elegans embryos [PDF]

, 2012
Accurate DNA replication requires proper regulation of replication licensing, which entails loading MCM-2-7 onto replication origins. In this paper, we provide the first comprehensive view of replication licensing in vivo, using video microscopy of ...
Anton Gartner, Ashley Craig, Baldinger, Blow, Blow, Brauchle, Brenner, Cheeseman, Chen, Clarey, Clarey, DePamphilis, Drury, Edgar, Encalada, Evrin, Galy, Gambus, Gillespie, Hadwiger, Harvey, Ilves, J. Julian Blow, Kamath, Kim, Kisielewska, Korzelius, Kuipers, Li, Li, Li, Liu, Matthieu Querenet, McNairn, McNally, Moyer, Oehlmann, Praitis, Prokhorova, Quinn, Randell, Remi Sonneville, Remus, Rothbauer, Rowles, Shelton, Siddiqui, Speck, Sönnichsen, Tada, Timmons, Waga, Wallenfang, Wohlschlegel, Yanagi, Yang, Zhong   +56 more
core   +4 more sources

Formulation and Biological Evaluation of Mesoporous Silica Nanoparticles Loaded with Combinations of Sortase A Inhibitors and Antimicrobial Peptides

Pharmaceutics, 2022
This study aimed to develop synergistic therapies to treat superbug infections through the encapsulation of sortase A inhibitors (SrtAIs; trans-chalcone (TC), curcumin (CUR), quercetin (QC), or berberine chloride (BR)) into MCM-41 mesoporous silica ...
Sitah Alharthi, Zyta M. Ziora, Taskeen Janjua, Amirali Popat, Peter M. Moyle   +4 more
doaj   +1 more source

Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme. [PDF]

, 2019
Cobamides, a uniquely diverse family of enzyme cofactors related to vitamin B12, are produced exclusively by bacteria and archaea but used in all domains of life.
Mok, Kenny, Park, Jong, Quanstrom, Kathryn, Sokolovskaya, Olga, Taga, Michi, Tran, Jennifer   +5 more
core   +1 more source

Effect of Lactation Age and Storage on the Antibacterial Potency of Human Breast Milk against Neonatal Pathogens

Journal of Pure and Applied Microbiology, 2018
The present study evaluates the effect of mothers lactation age and storage on the antibacterial potency of breast milk against common pathogens (E.coli, S.aureus and coagulase negative staphylococci) affecting newborns and toddlers.
Vandana Sharma, Chandni Sharma, Sunita Chauhan, Sandeep Kaur   +3 more
doaj   +1 more source

Indometacin loading and in vitro release properties from novel carbopol coated spherical mesoporous silica nanoparticles [PDF]

, 2013
Spherical MCM-41 silica nanosized particles were synthesized and post synthesis modified by 3-aminopropyltriethoxysilane (APTES) in order to prepare amino-functionalized carrier.
Agnes Szegedi, Basaldella, Borislav Tzankov, Chang, Chen, De Muth, Doadrio, Gao, Georgi Momekov, He, Hong, Horcajada, Huh, Judith Mihály, Kaneko, Konturek, Krassimira Yoncheva, Lai, Lee, Manzano, Manzano, Margarita Popova, Naito, Nicolai Lambov, Ogiso, Popova, Shorrock, Shrivastava, Slowing, Szegedi, Tan, Trewyn, Vallet-Regi, Wang, Wang, Yang, You   +36 more
core   +1 more source

Uncertainty Modeling and Evaluation of CMM Task Oriented Measurement Based on SVCMM

Measurement Science Review, 2017
Due to the variety of measurement tasks and the complexity of the errors of coordinate measuring machine (CMM), it is very difficult to reasonably evaluate the uncertainty of the measurement results of CMM. It has limited the application of CMM.
Li Hongli, Chen Xiaohuai, Cheng Yinbao, Liu Houde, Wang Hanbin, Cheng Zhenying, Wang Hongtao   +6 more
doaj   +1 more source

Why d-Mannose May Be as Efficient as Antibiotics in the Treatment of Acute Uncomplicated Lower Urinary Tract Infections—Preliminary Considerations and Conclusions from a Non-Interventional Study

Antibiotics, 2022
Urinary tract infections (UTIs) are very frequent in women and can be caused by a range of pathogens. High recurrence rates and increasing antibiotic resistance of uropathogens make UTIs a severe public health problem.
Florian Wagenlehner, Horst Lorenz, Oda Ewald, Peter Gerke   +3 more
doaj   +1 more source

Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication [PDF]

, 2015
© 2015, Chang et al.To initiate DNA replication, cells first load an MCM helicase double hexamer at origins in a reaction requiring ORC, Cdc6, and Cdt1, also called pre-replicative complex (pre-RC) assembly.
Speck, C
core   +1 more source

Mini-chromosome maintenance complexes form a filament to remodel DNA structure and topology. [PDF]

, 2013
Deregulation of mini-chromosome maintenance (MCM) proteins is associated with genomic instability and cancer. MCM complexes are recruited to replication origins for genome duplication.
Brewster, Aaron, Chen, Xiaojiang S, Forsburg, Susan L, Fu, Yang, Ranatunga, Nimna, Slaymaker, Ian M, Toso, Daniel B, Zhou, Z Hong   +7 more
core   +1 more source