Results 1 to 10 of about 1,341 (152)

The dose accumulation and the impact of deformable image registration on dose reporting parameters in a moving patient undergoing proton radiotherapy [PDF]

Radiology and Oncology, 2022
Potential changes in patient anatomy during proton radiotherapy may lead to a deviation of the delivered dose. A dose estimate can be computed through a deformable image registration (DIR) driven dose accumulation.
Razdevsek Gasper, Simoncic Urban, Snoj Luka, Studen Andrej   +3 more
doaj   +2 more sources

Capture-enhanced neutron irradiation to treat Alzheimer's disease: Design of a small animal set-up for future in-vivo experiments. [PDF]

Med Phys
Abstract BackgroundAlzheimer's disease (AD) is characterized by the accumulation of β$\beta$‐Amyloid and τ$\tau$ proteins in the brain that causes dementia. To date, there is no cure capable of eradicating AD, so it is necessary to study a performing therapy.
Pascali V, Tosoni D, Altieri S, Protti N.   +3 more
europepmc   +2 more sources

A comparative analysis of GEANT4, MCNP6 and FLUKA on proton-induced gamma-ray simulation. [PDF]

Med Phys
Abstract Background Precise range verification is essential in proton therapy to minimize treatment margins due to the steep dose fall‐off of proton beams. The emission of secondary radiation from nuclear reactions between incident particles and tissues stands out as a promising method for range verification. Two prominent techniques are PET and Prompt
Freitas H, Nobakht E, Grüner F, Seco J.
europepmc   +2 more sources

Advancing Internal Dosimetry in Personalized Nuclear Medicine: Toward Optimized Radiopharmaceutical Use in Clinical Practice [PDF]

Pharmaceuticals
Background: Quantifying absorbed doses from radiopharmaceuticals within human organs necessitates advanced computational modeling, as direct in vivo measurement remains impractical.
Ali H. D. Alshehri
doaj   +2 more sources

Advancing iris melanoma brachytherapy: Eye plaque models for Monte Carlo simulations and 3D dosimetric datasets. [PDF]

Med Phys
Abstract Purpose To develop and benchmark eye plaque models for Monte Carlo (MC) simulation of iris melanoma brachytherapy and to develop a database of 3D dose distributions for the iris plaques containing 103Pd${}^{103}{\rm Pd}$, 125I${}^{125}{\rm I}$, and 131Cs${}^{131}{\rm Cs}$ seeds.
Djedouani M, Viner A, Fletcher EM, Thomson RM.   +3 more
europepmc   +2 more sources

Generation of 3D reference dosimetric datasets towards adoption of model-based dose calculations for permanent implant prostate brachytherapy. [PDF]

Med Phys
Abstract Purpose This work aims to create and validate a comprehensive set of test cases and 3D reference dosimetric datasets for model‐based dose calculation algorithms (MBDCAs) in permanent implant prostate brachytherapy. These test cases address the limits of the standard TG‐43 formalism towards improving dose evaluations in prostate cancer ...
Akbari F, Peppa V, Ouellet S, Moghadam N, Oliver S, Gimenez-Alventosa V, Beaulieu L, Vijande J, Thomson RM.   +8 more
europepmc   +2 more sources

Shielding resources for four common radiopharmaceuticals utilized for imaging and therapy: Tc-99m, F-18, I-131, and Lu-177. [PDF]

J Appl Clin Med Phys
Abstract Introduction The use of radioactive materials in the United States has been tightly regulated by the Nuclear Regulatory Commission and other entities for many decades. In 2015, however, the Joint Commission began to require hospital‐based nuclear medicine departments to conduct shielding designs and evaluations for radioactive material areas ...
Oumano M, Wendt R, Botti J, Busse N, Hintenlang D, Leon S, Little K, Martin M, Massoth R, Matthews K, Prasad R, White S, Clements J.   +12 more
europepmc   +2 more sources

<i>Vitess 3.8</i>: a modernized framework for Monte Carlo neutron tracing simulations. [PDF]

J Appl Crystallogr
VITESS 3.8 introduces modernized neutron‐source modeling with new artificial‐intelligence‐based and KDSource modules, plus expanded component support including a prism module and NCrystal‐integrated sample module. It also delivers major upgrades to existing modules and multiple new features, advancing the simulation framework.VITESS is a modular Monte ...
Robledo JI, Violini N, Beule F, Voigt J, Zakalek P, Lieutenant K.   +5 more
europepmc   +2 more sources

Practical experience with initial quality assurance of a high dose rate brachytherapy grid-based Boltzmann solver algorithm. [PDF]

J Appl Clin Med Phys
Abstract Purpose The purpose of this study was to validate the use of a model‐based dose calculation algorithm (MBDCA), Acuros BV, for high dose rate brachytherapy treatment planning for a community‐based hospital with a Bravos afterloader. Based on published AAPM recommendations, this work details a practical approach for community‐based clinics to ...
Fagerstrom JM.
europepmc   +2 more sources

Estimating absorbed dose to breast adipose tissue from mammograms [PDF]

Journal of Medical Physics, 2021
Purpose Breast cancer usually originates in the glandular tissue of the breast. However, inflamed adipose tissue surrounding glandular tissue may expedite the local growth of cancerous cells.
Al Maqsudur Rashid, Rabin Dhakal, Hanna Moussa   +2 more
doaj   +2 more sources