Results 41 to 50 of about 13,872,257 (149)

Melanocortin receptor activation alleviates amyloid pathology and glial reactivity in an Alzheimer’s disease transgenic mouse model

Scientific Reports, 2021
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no disease-modifying treatment. AD progression is characterized by cognitive decline, neuroinflammation, and accumulation of amyloid-beta (Aβ) and neurofibrillary tangles in the ...
Jackie K. Y. Lau, Min Tian, Yang Shen, Shun-Fat Lau, Wing-Yu Fu, Amy K. Y. Fu, Nancy Y. Ip   +6 more
doaj   +1 more source

The relationship between motoric cognitive risk syndrome and all-cause mortality in older people: findings from CHARLS 2011–2023

Archives of Public Health
Background This study aims to investigate the association between motoric cognitive risk (MCR) syndrome, defined by the coexistence of slow gait and subjective cognitive complaints, and all-cause mortality among older adults in China, providing evidence ...
Xiang Li, Chao Wei, Kejing Hu, Jie Sun, Xiang Gao, Jianhong Yang   +5 more
doaj   +1 more source

Crystal Structure of the Catalytic Domain of MCR-1 (cMCR-1) in Complex with d-Xylose

Crystals, 2018
The polymyxin colistin is known as a “last resort” antibacterial drug toward pandrug-resistant enterobacteria. The recently discovered plasmid-encoded mcr-1 gene spreads rapidly across pathogenic strains and confers resistance to colistin, which has ...
Zhao-Xin Liu, Zhenggang Han, Xiao-Li Yu, Guoyuan Wen, Chi Zeng   +4 more
doaj   +1 more source

A Flexible Magnetically Controlled Continuum Robot Steering in the Enlarged Effective Workspace with Constraints for Retrograde Intrarenal Surgery

Advanced Intelligent Systems, 2021
Flexible magnetic continuum robots (MCRs) can be fabricated in small dimensions with great manipulability as their tips can deflect under fields, without the need for complicated mechanical structures to govern control, and it helps improve operating ...
Daojing Lin, Jingyi Wang, Niandong Jiao, Zhidong Wang, Lianqing Liu   +4 more
doaj   +1 more source

The association between sensory impairment and motoric cognitive risk syndrome in Chinese older adults

Guangxi Yike Daxue xuebao
Objective To explore the relationship between sensory impairment and motoric cognitive risk syndrome (MCR) in Chinese older adults. Methods Data from the China Health and Retirement Longitudinal Study (CHARLS) for the period 2011-2015 were utilized ...
LI Qi, ZHANG Weibo, JIA Feifei, JIA Cunxian   +3 more
doaj   +1 more source

mcr-3 positive bacteria

, 2019
detection of colistin-resistant mcr-positive bacteria in food-producing ...
USDA (17854931)
core  

MCR-1 Inhibition with Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Sensitivity to Polymyxin in Escherichia coli

mBio, 2017
In late 2015, the first example of a transferrable polymyxin resistance mechanism in Gram-negative pathogens, MCR-1, was reported. Since that report, MCR-1 has been described to occur in many Gram-negative pathogens, and the mechanism of MCR-1-mediated ...
Seth M. Daly, Carolyn R. Sturge, Christina F. Felder-Scott, Bruce L. Geller, David E. Greenberg   +4 more
doaj   +1 more source

Construction and Optimization of an Ecological Security Pattern Based on the MCR Model: A Case Study of the Minjiang River Basin in Eastern China. [PDF]

Int J Environ Res Public Health, 2022
Wang X, Xie X, Wang Z, Lin H, Liu Y, Xie H, Liu X.   +6 more
europepmc   +1 more source

Differential dementia risks of motoric cognitive risk syndrome and mild cognitive impairment among older adults in China: a 7-year cohort study

BMC Geriatrics
Background Mild cognitive impairment (MCI) and motoric cognitive risk syndrome (MCR) are two pre-dementia stages, which may exist independently or concurrently, and both increase the risk of dementia.
Bochao Niu, Dan Chen, Zhezhe Niu, Jian Wang   +3 more
doaj   +1 more source

Optimization of output power and transmission efficiency of magnetically coupled resonance wireless power transfer system

AIP Advances, 2018
Magnetically coupled resonance (MCR) wireless power transfer (WPT) system is a promising technology in electric energy transmission. But, if its system parameters are designed unreasonably, output power and transmission efficiency will be low. Therefore,
Rongge Yan, Xiaoting Guo, Shaoqing Cao, Changgeng Zhang   +3 more
doaj   +1 more source