Results 111 to 120 of about 33,511 (273)

Development of an Efficient and Scalable Process for Preparing Timolol N‐Nitrosamine Impurities B, C, E, H, I, J, and Their ADMET Evaluation

Journal of Heterocyclic Chemistry, EarlyView.
N‐nitrosamine impurities (B, C, E, H, I, J) of timolol maleate are easily synthesized from diethyl malonate and 3,4‐dichloro‐1,2,5‐thiadiazole. Good yields and precise impurity profiling are made possible by the effective technique, which also ensures pharmaceutical safety and strengthens regulatory compliance.
Kottolla Sai Prasad, Chithaluri Sudhakar, Vijaya Krishna Ravi, Bijaya Kethan Sahoo   +3 more
wiley   +1 more source

Limited Applicability of MOXY-Derived Muscle Oxygenation for Monitoring Upper-Body Strength Training

Applied Sciences
Objective: To determine the inter-session reliability of MOXY-derived muscle oxygenation (SmO2) in recreationally trained individuals during upper-body strength training.
Daniel Marcos-Frutos, Iago Rojas-Cepero, Antonio Martos-Arregui, Javier Rivero-Rodríguez, Amador García-Ramos   +4 more
doaj   +1 more source

Caracterización física de ligantes asfálticos con CECABASE para mezclas tibias [PDF]

, 2013
Reducir el consumo de energía así como las emisiones en la industria de la producción de mezclas asfálticas requiere la reducción de temperaturas de fabricación, las cuales tienden a perjudicar el rendimiento de la misma, por tal motivo el objetivo de ...
Casanova Torres, Sandra Lorena, Rodríguez Cabezas, Paola Katherine   +1 more
core  

Oral PHGG ameliorates atopic dermatitis‐like dermatitis with concurrent modulation of colonic IgA and cecal microbiota: implications for the gut–skin axis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Atopic dermatitis (AD) is increasingly recognized as a systemic inflammatory disorder linked to intestinal immune and microbiome dysregulation. However, whether dietary galactomannan fibers can mitigate AD through coordinated modulation of the gut–skin axis remains unexplored.
Derrick Kakooza, Hyeonjun Yu, Jonghyun Jeong, Jung Cheul Shin, Woo Jung Kim, Sung‐Kwon Moon, Hoon Kim   +6 more
wiley   +1 more source

Diagnóstico de las nuevas tecnologías empleadas para el diseño de mezclas asfálticas densas en caliente MDC-2

, 2012
El presente trabajo pretende brindar alternativas de modificación de las Mezclas Asfálticas Densas en Caliente, empleadas para la pavimentación de las vías en Colombia, mecanismos que actualmente generan un impacto ambiental negativo debido a la utilización de los materiales pétreos, los cuales debido a su ubicación no cumplen con las especificaciones ...
Camargo Chávez, Hugo Erney, Suárez Mesa, Andrea Del Pilar   +1 more
openaire   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source

Accuracy and repeatability of the COSMED® Q-NRG max mobile metabolic system.

PLoS ONE
PurposeTo investigate the accuracy and repeatability of the Q-NRG Max® metabolic system against a VacuMed metabolic simulator using a wide range of metabolic rates.MethodsSixteen metabolic rates (oxygen consumption 0.9-6 L/min), with different ...
Lavinia Falcioni, Laura Guidetti, Carlo Baldari, Andrey Sanko Posada, Chris Wing, Luke Dover, Marco Meucci   +6 more
doaj   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

Mass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Comportamiento monotónico de mezclas asfálticas MDC-2 adicionadas con desecho de caucho-cuero

Academia y Virtualidad, 2013
El objetivo de ésta investigación fue determinar el comportamiento monotónico de mezclas asfálticas MDC-2 con adición de grano de caucho-cuero en relación con las mezclas asfálticas fabricadas convencionalmente, teniendo en cuenta los parámetros de estabilidad y deformación.
openaire   +1 more source

Defining Quality of Life: The Perspective of People Living with Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Little is known about how people with Parkinson's conceptualize “quality of life.” Objective To describe the meaning of “quality of life” from the perspective of people with Parkinson's. Methods Participants (N = 42) were asked “What does the term ‘quality of life’ mean to you?” Definitions were analyzed using inductive qualitative ...
Samantha Dorrance, Richa Patel, Glenn T. Stebbins, Jamie L. Adams, Allison M. Allen, Tara Hastings, Soania Mathur, Onanong Phokaewvarangkul, Gary Rafaloff, Rajasumi Rajalingam, Anette Schrag, Christine Sun, Jennifer Mammen, Connie Marras   +13 more
wiley   +1 more source