Results 61 to 70 of about 33,511 (273)

Dynamo and Electrical Jet in Hall Plasmas, Application to Astrophysics

, 2001
The magnetic field in Hall plasmas is frozen in the electron component and is advected not only with the plasma motion but also with the electrical current flow. Its coupling with the plasma may be not as strong as characteristic of the MHD approximation.
Rudakov, L. I.
core   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

Low-grade inflammation in type 2 diabetes: a cross-sectional study from a Danish diabetes outpatient clinic

BMJ Open, 2022
Objectives To investigate low-grade inflammation in type 2 diabetes and explore associations to clinical aspects as well as microvascular and macrovascular complications.Design Cross-sectional analysis.Setting The outpatient diabetes clinic at the ...
Joachim Størling, Christina Brock, Tina Okdahl, Birgitte Brock, Flemming Pociot, Anne-Marie Wegeberg   +5 more
doaj   +1 more source

Heterotic Cosmic Strings [PDF]

, 2005
We show that all three conditions for the cosmological relevance of heterotic cosmic strings, the right tension, stability and a production mechanism at the end of inflation, can be met in the strongly coupled M-theory regime.
A. A. Abrikosov, A. A. Abrikosov, A. C. Davis, Axel Krause, E. I. Buchbinder, F. R. Bouchet, Katrin Becker, Melanie Becker, S. Raby, T. Friedmann   +9 more
core   +3 more sources

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Validity, reliability and minimum detectable change of COSMED K5 portable gas exchange system in breath-by-breath mode.

PLoS ONE, 2018
PurposeThis study aimed to examine the validity, reliability and minimum detectable change (MDC) of the Cosmed K5 in breath by breath (BxB) mode, against VacuMed metabolic simulator.
Laura Guidetti, Marco Meucci, Francesco Bolletta, Gian Pietro Emerenziani, Maria Chiara Gallotta, Carlo Baldari   +5 more
doaj   +1 more source

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Transformation of a state fish and wildlife agency: Missouri Department of Conservation's effort to remain relevant in a changing world

Conservation Science and Practice, 2022
In 1935, the citizens of Missouri established the Missouri Conservation Commission in the state's constitution and in 1976 approved a conservation sales tax to ensure sustainable funding for those priorities.
Sara Parker Pauley, Audrey Beres, Norman Murray, Jason A. Sumners, Kendra Witthaus, Kristie Hilgedick   +5 more
doaj   +1 more source

Orchestrated Engineered Polyphenol‐Peptide Condensates Coupled With β‐GP Reverses Diabetic Osteoporosis by Remodeling Mitophagy

Advanced Science, EarlyView.
A multifunctional β‐GP@EGCG‐E7 nanoplatform is engineered by polyphenol–peptide condensation and phosphate loading. Bone‐targeted delivery, antioxidant and anti‐inflammatory activity, and mitophagy restoration are integrated in one system, enabling protection of osteoblasts and endothelial cells and promoting bone regeneration under diabetic ...
Xiuyun Xu, Meiqin Zhang, Ting Wu, Erfan Wei, Andrei Y. Hancharou, Zeying Wang, Zijuan Wang, Letian Lv, Likun Wu, Xingtong Pan, Qiyue Zhu, Xinyi Dong, Hao Liu, Yongsheng Zhou   +13 more
wiley   +1 more source

Influence of the environmental conditions of Bogotá on the Marshall Stability and flow of a hot mix asphalt [PDF]

, 2008
Influencia de las condiciones ambientales de la ciudad de Bogotá sobre la estabilidad y el flujo Marshall de una mezcla densa en caliente El artículo presenta el cambio que experimentan los parámetros de estabilidad y flujo del ensayo Marshall de mezclas
Moreno-Anselmi, Luis Ángel, Pinzón-Hernández, Miguel Hernesto, Reyes-Lizcano, Fredy Alberto, Rondón-Quintana, Hugo Alexander, Vacca-Gámez, Hermes Ariel, Vargas-Arenas, Xiomara Andrea   +5 more
core   +1 more source