Results 221 to 230 of about 2,782,523 (317)

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Image-based explainable artificial intelligence accurately identifies myelodysplastic neoplasms beyond conventional signs of dysplasia. [PDF]

NPJ Precis Oncol
Eckardt JN, Srivastava I, Schulze F, Winter S, Schmittmann T, Riechert S, Schneider MMK, Reichel L, Gediga MEH, Sockel K, Sulaiman AS, Röllig C, Kroschinsky F, Asemissen AM, Pohlkamp C, Haferlach T, Bornhäuser M, Wendt K, Middeke JM.   +18 more
europepmc   +1 more source

Organelle Localization‐Induced Bio‐Orthogonal Polymerization (OLIBOP) for Photostable Super‐Resolution Live‐Cell Imaging

Advanced Healthcare Materials, EarlyView.
Organelle localization‐induced biorthogonal polymerization enables direct synthesis of photostable poly‐AIEgens within targeted organelles for super‐resolution live‐cell imaging. ABSTRACT Real‐time monitoring of dynamic biological processes demands fluorescent probes that can withstand prolonged light exposure without photobleaching—a critical ...
Gaeun Park, Sangpil Kim, Dohyun Kim, Injun Hwang, Ja‐Hyoung Ryu   +4 more
wiley   +1 more source

Association of neurogenic orthostatic hypotension with cognitive decline in Parkinson's disease: a longitudinal cohort study. [PDF]

Front Neurol
Bagheri N, Longardner K, Coughlin D.
europepmc   +1 more source

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

Advanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou, Barbara Spagnolo, Antonio Balena, Massimo De Vittorio, Ferruccio Pisanello   +4 more
wiley   +1 more source

MD code for phoresis

Report describing the functioning of a code adapted to simulate phoresis under general ...
openaire   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Transcranial temporal interference stimulation targeting the subthalamic region for motor symptoms in Parkinson's disease: a pilot, randomised, double-blind, sham-controlled crossover study. [PDF]

EBioMedicine
Yang C, Xu Y, Du Y, Shen X, Li T, Chen N, Zhu Y, Huang L, Lü J, Li L, Qian Z, Wang Z, Ziemann U, Grossman N, Pascual-Leone A, Manor B, Zhang C, Zhou J, Liu Y.   +18 more
europepmc   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Protocol to investigate fibroblastic reticular cell-immune cell interaction in human lung cancer. [PDF]

STAR Protoc
Papadopoulou C, Cheng HW, Lütge A, Lütge M, De Martin A, Robinson MD, Ludewig B, Onder L.   +7 more
europepmc   +1 more source