Results 121 to 130 of about 35,611 (258)
Reversible codes in the Rosenbloom-Tsfasman metric
Reversible codes have a range of wide applications in cryptography, data storage, and communication systems. In this paper, we investigated reversible codes under the Rosenbloom-Tsfasman metric (RT-metric).
Bodigiri Sai Gopinadh +1 more
doaj +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Research on fractional repetition codes based on group divisible designs
A novel design of FR (fractional repetition) codes was proposed which aims at providing efficient repair at the minimum bandwidth regenerating point.The design consisted of an outer MDS (maximum distance separable) code and an inner repetition code ...
Bing ZHU +4 more
doaj +2 more sources
Complementarity of Long‐Reads and Optical Mapping in Parkinson's Disease for Structural Variants
ABSTRACT Objective Long‐read sequencing and optical genome mapping technologies have the ability to detect large and complex structural variants. This has led to the discovery of novel pathogenic variants in neurodegenerative movement disorders. Thus, we aimed to systematically compare the SV detection capabilities of OGM and ONT in Parkinson's disease.
André Fienemann +17 more
wiley +1 more source
BackgroundCardiopulmonary resuscitation (CPR) use with no considerations given to patient selection or therapeutic aim resulted in extension of the agony, pain and dying process for terminally ill patients.
Raymonda Chahrour +6 more
doaj +1 more source
We report the national burden of dermatopolymyositis mortality over the past quarter century using the US national vital statistics data. Age‐standardized mortality rates for dermatopolymyositis decreased at an annual rate of 3.8% each year, which was higher than the annual percent decrease for deaths from all other causes.
Elizabeth Matz, Ram R. Singh
wiley +1 more source
Decoding of MDP Convolutional Codes over the Erasure Channel under Linear Systems Point of View
This paper attempts to highlight the decoding capabilities of MDP convolutional codes over the erasure channel by defining them as discrete linear dynamical systems, with which the controllability property and the observability characteristics of linear ...
Maria Isabel García-Planas +1 more
doaj +1 more source
Objective This study aimed to evaluate the impact of a series of policies that mandated switching patients with inflammatory arthritis (IA) from an originator biologic to a biosimilar in British Columbia, Canada, on health care resource use and cost.
HaoHung Dang +4 more
wiley +1 more source
Objective In complex diseases, it is challenging to assess a patient's disease state, trajectory, treatment exposures, and risk of multiple outcomes simultaneously, efficiently, and at the point of care. Methods We developed an interactive patient‐level data visualization and analysis tool (VAT) that automates illustration of the trajectory of a ...
Ji Soo Kim +18 more
wiley +1 more source

