Results 61 to 70 of about 35,366 (273)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

MDS Self-Dual Codes and Antiorthogonal Matrices over Galois Rings

Information, 2019
In this study, we explore maximum distance separable (MDS) self-dual codes over Galois rings G R ( p m , r ) with p ≡ − 1 ( mod 4 ) and odd r.
Sunghyu Han
doaj   +1 more source

Additive MDS codes

, 2022
We prove that an additive code over a finite field which has a few projections which are equivalent to a linear code is itself equivalent to a linear code, providing the code is not too short.
Ball, Simeon Michael, Adriaensen, Sam
openaire   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Decoding of Convolutional Codes over the Erasure Channel

, 2011
In this paper we study the decoding capabilities of convolutional codes over the erasure channel. Of special interest will be maximum distance profile (MDP) convolutional codes. These are codes which have a maximum possible column distance increase.
Rosenthal, Joachim, Smarandache, Roxana, Tomás, Virtudes   +2 more
core   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

On Group Codes Over Elementary Abelian Groups

Sultan Qaboos University Journal for Science, 2003
For group codes over elementary Abelian groups we present definitions of the generator and the parity check matrices, which are matrices over the ring of endomorphism of the group.
Adnan A. Zain
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Direct Construction of Optimal Rotational-XOR Diffusion Primitives

IACR Transactions on Symmetric Cryptology, 2017
As a core component of SPN block cipher and hash function, diffusion layer is mainly introduced by matrices built from maximum distance separable (MDS) codes.
Zhiyuan Guo, Renzhang Liu, Si Gao, Wenling Wu, Dongdai Lin   +4 more
doaj   +1 more source