Results 221 to 230 of about 38,496 (259)
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Studies of mdx mice

Neuroscience, 2004
Cerebral water accumulation-clinically denoted as brain edema-is a potentially life threatening complication of almost every intracranial neuropathological state. The molecular membrane water channel aquaporin-4 (AQP4) has been shown to be present at the blood-brain barrier (BBB) where it plays pivotal role in the transport of water between the tissue ...
Vajda, Z.   +4 more
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Mdx muscle grafts retain the mdx phenotype in normal hosts

Muscle & Nerve, 1989
AbstractWhole muscle grafts were made between mdx and normal mice to investigate whether the mdx myopathic lesion is intrinsic to mdx muscle or is a property of its environment. Grafts were examined between 20 and 101 days. Unequivocal necrotic muscle fibers and/or newly formed basophilic myotubes were noted in 8 of 16 grafts of mdx muscle made in ...
J E, Morgan   +2 more
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Neurocognitive Impairment in mdx Mice

Molecular Neurobiology, 2019
Duchenne muscular dystrophy (DMD) is a neuromuscular disorder that affects muscles and also the brain, resulting in memory and behavioral problems. In the pathogenesis of DMD, inflammation is an important factor during the degenerative process. However, the involvement of the brain is still unclear. Therefore, the objective of this study is to evaluate
Clarissa M. Comim   +11 more
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Posttetanic potentiation in mdx muscle

Journal of Muscle Research and Cell Motility, 2010
X-linked muscular dystrophy of the mouse (mdx) has been reported to progressively remodel skeletal muscle to preferentially reduce fast fiber composition. Despite this, mdx muscle displays normal levels of posttetanic potentiation (PTP). Since PTP may primarily depend on phosphorylation of the myosin regulatory light chain (RLC) in fast muscle fibers ...
Ian Curtis, Smith   +4 more
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Genetically dystrophic mdx/mdx mice exhibit decreased response to nicotine in passive avoidance

Neuroreport, 2002
mdx mice are considered as a genetic homologous of human Duchenne muscular dystrophy. Recent evidence demonstrates that in mouse sympathetic ganglion dystrophin is involved in the stabilization of nicotinic acetylcholine receptor clusters. The purpose of this study was to verify possible effects of dystrophin alterations at the central level.
Roberto Coccurello   +4 more
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Introduction to MDX

2011
In this chapter, you’ll work with Multidimensional Expressions (MDX), which is the native query language for SQL Server Analysis Services (SSAS). MDX is a SQL-like language used to query SSAS cubes.
Guy Fouché, Lynn Langit
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Recursion in MDX

2002
The term ‘recursion’ is used to describe something that references itself. My favorite definition of recursion is found in the joke.
Mark Whitehorn   +2 more
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Dystrophin distribution in heterozygote mdx mice

Muscle & Nerve, 1989
AbstractThe distribution of dystrophin in myofibers from normal, mdx hemizygous, and mdx heterozygous mice was studied at various times in development. While normal mice exhibit dystrophin immunostaining around the entire fiber periphery regardless of age, mdx hemizygous mice exhibit no staining (0–35 days). In contrast, young (10 day) heterozygous mdx
S C, Watkins   +3 more
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Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice

American Journal of Physiology-Cell Physiology, 1997
Diaphragm muscles of young (4- to 6-mo-old) mdx mice show severe fiber necrosis and have normalized forces and powers 60 and 46% of the values for control C57BL/10 mice. In contrast, microinjection of mdx mouse embryos with a truncated dystrophin minigene has produced young transgenic mdx (tg-mdx) mice with a level of dystrophin expression and ...
G S, Lynch   +5 more
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MDX-060. Medarex.

Current opinion in investigational drugs (London, England : 2000), 2006
Medarex is developing the antibody MDX-060 for the potential treatment of CD30+ lymphomas, such as Hodgkin's disease and anaplastic large cell lymphomas. Phase I/II clinical trials were underway by December 2002.
Xiu Feng, Hu, Pei Xiang, Xing
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