Results 221 to 230 of about 38,378 (273)

Recursion in MDX

2002
The term ‘recursion’ is used to describe something that references itself. My favorite definition of recursion is found in the joke.
Mark Whitehorn, Robert Zare, Mosha Pasumansky   +2 more
openaire   +1 more source

Dystrophin distribution in heterozygote mdx mice

Muscle & Nerve, 1989
AbstractThe distribution of dystrophin in myofibers from normal, mdx hemizygous, and mdx heterozygous mice was studied at various times in development. While normal mice exhibit dystrophin immunostaining around the entire fiber periphery regardless of age, mdx hemizygous mice exhibit no staining (0–35 days). In contrast, young (10 day) heterozygous mdx
S C, Watkins, E P, Hoffman, H S, Slayter, L M, Kunkel   +3 more
openaire   +2 more sources

Contractile properties of diaphragm muscle segments from old mdx and old transgenic mdx mice

American Journal of Physiology-Cell Physiology, 1997
Diaphragm muscles of young (4- to 6-mo-old) mdx mice show severe fiber necrosis and have normalized forces and powers 60 and 46% of the values for control C57BL/10 mice. In contrast, microinjection of mdx mouse embryos with a truncated dystrophin minigene has produced young transgenic mdx (tg-mdx) mice with a level of dystrophin expression and ...
G S, Lynch, J A, Rafael, R T, Hinkle, N M, Cole, J S, Chamberlain, J A, Faulkner   +5 more
openaire   +2 more sources

MDX-060. Medarex.

Current opinion in investigational drugs (London, England : 2000), 2006
Medarex is developing the antibody MDX-060 for the potential treatment of CD30+ lymphomas, such as Hodgkin's disease and anaplastic large cell lymphomas. Phase I/II clinical trials were underway by December 2002.
Xiu Feng, Hu, Pei Xiang, Xing
openaire   +1 more source

Neuromuscular transmission in the mdx mouse

Muscle & Nerve, 1990
AbstractThe mdx mouse is an animal model for human Duchenne dystrophy. In both disorders, the muscle fiber plasma membrane is rendered selectively vulnerable by dystrophin deficiency. In both disorders there are also ultrastructural abnormalities involving the postsynaptic membrane of the neuromuscular junction.
A, Nagel, F, Lehmann-Horn, A G, Engel
openaire   +2 more sources

Dystrophin in control and mdx retina

Brain and Development, 1991
To determine whether or not dystrophin really exists in the outer plexiform layer (OPL) of the retina, we studied control and mdx mice, using four kinds of polyclonal antibodies (DMDP-II, 60 kd, 30 kd and DMDP-IV) against dystrophin. Although control OPL showed a positive immunohistochemical reaction with all four antibodies, mdx OPL showed a positive ...
J, Zhao, M, Uchino, K, Yoshioka, M, Miyatake, T, Miike   +4 more
openaire   +2 more sources

Muscle development in mdx mutant mice

Muscle & Nerve, 1984
AbstractMechanical and contractile properties of tibialis anterior (TA) muscles from X‐linked muscular dystrophic (mdx) mutant mice at different stages of development are compared to those of muscles from normal control animals. There is no difference between the tension output, speeds of contraction and relaxation, and weight of TA muscles from mutant
J, Dangain, G, Vrbova
openaire   +2 more sources

Muscular weakness in the mdx mouse

Journal of the Neurological Sciences, 1993
mdx mice are believed to be virtually free from neuromuscular symptoms, despite the presence of a degenerative/regenerative process that involves all skeletal muscles. We analyzed both the spontaneous motility and treadmill motor activity of mdx mice aged 15 days to 6 months.
Muntoni F., Mateddu A., Marchei F., Clerk A., SERRA, Gino   +4 more
openaire   +3 more sources

Running endurance abnormality in mdx mice

Muscle & Nerve, 2002
AbstractThe mdx mouse lacks dystrophin and has histological features of Duchenne muscular dystrophy but little weakness in the first year of life. We report here an early deficit in voluntary wheel running, as assayed with a computerized wheel. All mdx mice showed an intermittent running pattern, in contrast to the continuous running seen in controls ...
Hajime, Hara, Patrick M, Nolan, Marion O, Scott, Maja, Bucan, Yoshihiro, Wakayama, Kenneth H, Fischbeck   +5 more
openaire   +2 more sources

Text-to-MDX: LLM-Assisted Generation of MDX Queries from User Questions

MDX (MultiDimensional Expressions) is the standard language for querying multidimensional data in OLAP systems, but its complex syntax poses challenges for non-expert users. While a lot of research has focused on natural language interfaces for SQL, little attention has been given to MDX. This paper explores the potential of Large Language Models (LLMs)
Sandro Bimonte, Stefano Rizzi
openaire   +2 more sources