Results 101 to 110 of about 1,087,549 (254)
Skeletal Muscle, 2017 Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin expression and leads to severe ambulatory and cardiac function decline. However, the dystrophin-deficient mdx murine model of DMD only develops a very mild form of the disease.
Nadia Milad +5 more
semanticscholar +1 more source
The Landscape of SPP1 + Macrophages Across Tissues and Diseases: A Comprehensive Review
Immunology, Volume 176, Issue 2, Page 179-196, October 2025.SPP1+ macrophages represent a conserved, disease‐associated population present across cancerous and non‐cancerous conditions, involved in immunosuppression, fibrosis, lipid metabolism, phagocytosis, and other cellular processes. This review highlights their shared molecular programmes across tissues, their interactions with stromal and immune cells ...
Alessandro Palma
wiley +1 more source
BMC Neuroscience, 2017 In Duchenne muscular dystrophy (DMD), the loss of the dystrophin component of the dystrophin-glycoprotein complex (DGC) compromises plasma membrane integrity in skeletal muscle, resulting in extensive muscle degeneration.
Azeez Aranmolate +2 more
semanticscholar +1 more source
The Journal of Physiology, Volume 603, Issue 19, Page 5273-5297, October 1, 2025.Abstract figure legend Fibro/adipogenic progenitors (FAPs) are cells resident in the muscle (skeletal and cardiac) niche. FAPs are active participants in the process of muscle degeneration in cardiovascular and neuromuscular diseases. Here, the accumulation of fatty and fibrous tissue is a hallmark.
Elisa Villalobos +2 more
wiley +1 more source
Disuse‐induced muscle‐type specific alterations and adiponectin pathway response in male mice
Physiological Reports, Volume 13, Issue 20, October 2025.(LeftPanel) HindLimb Unloading combined with Immobilization (HLUI) was used to induce Disuse Muscle Atrophy (DMA) via an optimized device that allow mouse displacements along the cage. As a result of muscle positioning during immobilization, the Soleus muscle was stretched and the Tibialis anterior (TA) muscle was shortened.
Szczepanski Sébastien +5 more
wiley +1 more source
Mechanical and energetic properties of dystrophic (mdx) mouse muscle.
The Japanese Journal of Physiology, 1990 The mechanical and energetic properties of extensor digitorum longus (EDL) and soleus muscles of X chromosome-linked muscular dystrophic mutant (mdx) mice aged 4-6 weeks were studied and compared with those of the muscles of normal mice. Maximum tetanic tension, the speed of contraction of relaxation, and the heat production of mdx soleus muscles were ...
Kazuhiro Yamada +2 more
openaire +4 more sources
The FASEB Journal, Volume 39, Issue 18, 30 September 2025.Spontaneous locomotor activity of Duchenne muscular dystrophy (DMD) model mice was monitored using a cage system with external sensors. Mice received oral United State Pharmacopeia‐grade N‐acetylglucosamine (GlcNAc), prednisolone (Pred)—a current standard of care for DMD—or a combination of both.
Masahiko. S. Satoh +4 more
wiley +1 more source
Neurobiology of Disease, 2008 We previously reported that in the superior cervical ganglion (SCG) of dystrophic mdx mice, which lack full-length dystrophin, there is a loss of neurons projecting to SCG muscular targets, like the iris.
Loredana Lombardi +2 more
doaj +1 more source
PLOS Currents, 2017 Introduction: Duchenne Muscular Dystrophy (DMD) is a debilitating muscle wasting disorder with no cure. Safer supplements and therapies are needed to improve the severity of symptoms, as severe side effects are associated with the only effective ...
R. G. Barker +3 more
semanticscholar +1 more source
Molecular Autism, 2015 BackgroundThe Duchenne and Becker muscular dystrophies (DMD, BMD) show significant comorbid diagnosis for autism, and the genomic sequences encoding the proteins responsible for these diseases, the dystrophin and associated proteins, have been proposed ...
R. Miranda +5 more
semanticscholar +1 more source