Results 131 to 140 of about 1,087,549 (254)

Comparative lipidomic and metabolomic profiling of mdx and severe mdx-apolipoprotein e-null mice

Skeletal Muscle
Despite its notoriously mild phenotype, the dystrophin-deficient mdx mouse is the most common model of Duchenne muscular dystrophy (DMD). By mimicking a human DMD-associated metabolic comorbidity, hyperlipidemia, in mdx mice by inactivating the ...
Ram B. Khattri, Abhinandan Batra, Zoe White, David Hammers, Terence E. Ryan, Elisabeth R. Barton, Pascal Bernatchez, Glenn A. Walter   +7 more
doaj   +1 more source

Six weeks of N-acetylcysteine antioxidant in drinking water decreases pathological fiber branching in MDX mouse dystrophic fast-twitch skeletal muscle. [PDF]

Front Physiol, 2023
Redwan A, Kiriaev L, Kueh S, Morley JW, Houweling P, Perry BD, Head SI.   +6 more
europepmc   +1 more source

Morpholino antisense oligonucleotide induced dystrophin exon 23 skipping in mdx mouse muscle [PDF]

, 2003
B L Gebski, C. J. Mann, Sue Fletcher, Steve D. Wilton   +3 more
openalex   +1 more source

Prolonged dystrophin expression and functional correction of mdx mouse muscle following gene transfer with a helper-dependent (gutted) adenovirus-encoding murine dystrophin [PDF]

, 2003
Rénald Gilbert, Roy Dudley, An‐Bang Liu, Basil J. Petrof, Joséphine Nalbantoglu, George Karpati   +5 more
openalex   +1 more source

Tissue distribution of the dystrophin-related gene product and expression in the mdx and dy mouse.

, 1991
Donald R. Love, Glenn E. Morris, J M Ellis, U. L. Fairbrother, Rosalind F. Marsden, J.F. Bloomfield, Yvonne H. Edwards, C P Slater, David Parry, Kay E. Davies   +9 more
openalex   +1 more source

254. AAV Mediated Co-Delivery of Igf-I and Dystrophin to mdx Mouse Muscle [PDF]

, 2003

openalex   +1 more source

Mineralocorticoid receptor antagonists reduce inflammatory signaling independent of myofiber mineralocorticoid receptor

Endocrine and Metabolic Science
Chronic inflammation is a feature of Duchenne muscular dystrophy (DMD), a degenerative striated muscle disease. Mineralocorticoid receptor (MR) antagonists (MRAs) have demonstrated clinical benefit on later onset DMD cardiomyopathy, and preclinical ...
Jeovanna Lowe, Arden B. Piepho, Chetan K. Gomatam, Peyton Debell, Megan N. Ballinger, Jill A. Rafael-Fortney   +5 more
doaj   +1 more source

Sunitinib inhibits STAT3 phosphorylation in cardiac muscle and prevents cardiomyopathy in the mdx mouse model of Duchenne muscular dystrophy. [PDF]

Hum Mol Genet, 2022
Oliveira-Santos A, Dagda M, Burkin DJ.
europepmc   +1 more source

FORMATION of DYSTROPHIN-POSITIVE MUSCLE FIBERS IN THE MDX MOUSE BY C2 MYOBLAST TRANSFER.

, 1994
Yasuko Haeiwara, Yuji Mizuno, Masakazu Takemitsu, Ikuya Nonaka, Eijiro Ozawa   +4 more
openalex   +1 more source

Respiratory pathology in the mdx/utrn -/- mouse: A murine model for Duchenne Muscular Dystrophy (DMD).

PLoS ONE
Duchenne muscular dystrophy (DMD) is an X-linked devastating disease caused by a lack of dystrophin which results in progressive muscle weakness. As muscle weakness progresses, respiratory insufficiency and hypoventilation result in significant morbidity
Marán Y Hernández Rodríguez, Debolina D Biswas, Aoife D Slyne, Jane Lee, Evelyn Scarrow, Sarra M Abdelbarr, Heather Daniels, Ken D O'Halloran, Leonardo F Ferreira, Charles A Gersbach, Mai K ElMallah   +10 more
doaj   +1 more source