Results 81 to 90 of about 9,256 (223)

The Female mdx Mouse: An Unexpected Vascular Story [PDF]

Journal of Neurology and Neuromedicine, 2016
Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disease, caused by absence of functional dystrophin and inevitably leading to death. A variable proportion of women carriers (2.5 to 19%) can also manifest symptoms ranging from myalgia to cardiomyopathy, and pathophysiological mechanisms are still not completely understood.
openaire   +1 more source

Live‐imaging of revertant and therapeutically restored dystrophin in the Dmd^EGFP‐mdx mouse model for Duchenne muscular dystrophy [PDF]

, 2020
Mina Petkova, Amalia Stantzou, A. Morin, Olga N. Petrova, Susanne Morales-Gonzalez, Franziska Seifert, J. Bellec-Dyèvre, Tudor Manoliu, Aurélie Goyenvalle, Laurynn Garcia, Isabelle Richard, Corinne Laplace‐Builhé, Markus Schuelke, Helge Amthor   +13 more
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Brain glucose metabolism as a neuronal substrate of the abnormal behavioral response to stress in the mdx mouse, a model of Duchenne muscular dystrophy

Neurobiology of Disease
Duchenne muscular dystrophy (DMD) is associated with a range of cognitive and behavioral problems. Brain-related comorbidities show clinical heterogeneity depending on the position of the mutation within the multi-promoter dystrophin (DMD) gene, likely ...
Sébastien Goutal, Marion Lancien, François Rivier, Nicolas Tournier, Cyrille Vaillend   +4 more
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Towards developing standard operating procedures for pre-clinical testing in the mdx mouse model of Duchenne muscular dystrophy

Neurobiology of Disease, 2008
This review discusses various issues to consider when developing standard operating procedures for pre-clinical studies in the mdx mouse model of Duchenne muscular dystrophy (DMD).
Miranda D. Grounds, Hannah G. Radley, Gordon S. Lynch, Kanneboyina Nagaraju, Annamaria De Luca   +4 more
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573. Enhanced Level of Gene Correction Mediated by Oligonucleotides Containing CpG Modification in the mdx Mouse Model for Duchenne Muscular Dystrophy [PDF]

, 2006
Carmen Bertoni, Arjun Rustagi, Thomas A. Rando   +2 more
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PKC theta ablation improves healing in a mouse model of muscular dystrophy.

PLoS ONE, 2012
Inflammation is a key pathological characteristic of dystrophic muscle lesion formation, limiting muscle regeneration and resulting in fibrotic and fatty tissue replacement of muscle, which exacerbates the wasting process in dystrophic muscles.
Luca Madaro, Andrea Pelle, Carmine Nicoletti, Annunziata Crupi, Valeria Marrocco, Gianluca Bossi, Silvia Soddu, Marina Bouché   +7 more
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Failure to resolve inflammation contributes to juvenile onset cardiac damage in a mouse model of Duchenne muscular dystrophy

Cell Death and Disease
Absence of dystrophin protein causes cardiac dysfunction in patients with Duchenne muscular dystrophy (DMD). Unlike boys with DMD, the common mouse model of DMD (B10-mdx) does not manifest cardiac deficits until late adulthood.
James S. Novak, Amy Lischin, Prech Uapinyoying, Ravi Hindupur, Young Jae Moon, Surajit Bhattacharya, Sarah Tiufekchiev-Grieco, Victoria Barone, Davi A. G. Mázala, Iteoluwakishi H. Gamu, Gabriela Walters, Jyoti K. Jaiswal   +11 more
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Dietary Phosphorus Overload Aggravates the Phenotype of the Dystrophin-Deficient mdx Mouse [PDF]

, 2014
E. Wada, Mizuko Yoshida, Yoriko Kojima, Ikuya Nonaka, Kazuya Ohashi, Yosuke Nagata, Masataka Shiozuka, Munehiro Date, Tetsuo Higashi, Ichizo Nishino, Ryoichi Matsuda   +10 more
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P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment [PDF]

, 2011
Chris Young, Wojciech Brutkowski, Chun‐Fu Lien, S. Arkle, Hanns Lochmüller, Krzysztof Zabłocki, Dariusz C. Górecki   +6 more
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Dystrophin Cytochemistry in Mdx Mouse Muscles Injected with Labeled Normal Myoblasts

Cell Transplantation, 1992
A new technique enables correlation of dystrophin expression with the location of donor versus host nuclei in the same sections of mdx mouse muscle injected with normal myoblasts. Myoblasts from C57BL/6J mice or from humans were labeled with 0.01% fluoro-
Ming Chen, Hua-Ju Li, Qiuwen Fang, Tena G. Goodwin, J. Ann Florendo, Peter K. Law   +5 more
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