Results 11 to 20 of about 17,990 (247)

Optimization of courses offer in educational institutions

Revista de Matemática: Teoría y Aplicaciones, 2015
In the problem of scheduling of courses, it is generally assumed that the allocation of subjects to teaching periods is an input of the problem, which is defined by the academic authorities.
Rafael López Bracho, Angélica Iliana Granados Ochoa, Mirelle Hernández Fragoso   +2 more
doaj   +1 more source

El “coto vedado” de la democracia y las restricciones jurídicas a la consulta popular en México: los derechos humanos y la voluntad republicana

Pensamiento Americano, 2018
El objetivo primordial de este artículo es presentar la relación existente entre las categorías principales de la teoría democrática del Coto Vedado y las restricciones jurídicas establecidas constitucional y legalmente al derecho político de consulta ...
Joaquín Ordóñez, Enrique Uribe Arzate   +1 more
doaj   +1 more source

Mesorhizobium septentrionale sp nov and Mesorhizobium temperatum sp nov., isolated from Astragalus adsurgens growing in the northern regions of China [PDF]

, 2004
Ninety-five rhizobial strains isolated from Astragalus adsurgens growing in the northern regions of China were classified into three main groups, candidate species 1, 11 and 111, based on a polyphasic approach.
Allen, Chen, Chen, Chen, Chen, de Lajudie, de Lajudie, De Ley, En Tao Wang, Feng Ling Kan, Gao, Gao, Gaunt, Graham, Guo, Hurek, J. Peter W. Young, Jarvis, Jun Gu, Jun-Lian Gao, Kristina Lindström, Laguerre, Li, Marmur, Marmur, Martínez-Romero, Nagasawa, Page, Peng, Sarah Lea Turner, Shon, Sneath, Sriprang, Sullivan, Tan, Thompson, Turner, Velázquez, Vincent, Wang, Wang, Wayne, Wdowiak, Wen Xin Chen, Xu, Yu Hui Qiu, Zewdu Terefework, Zhang, Zhi Yuan Tan   +48 more
core   +1 more source

The tyrosine kinase FER is responsible for the capacitation-associated increase in tyrosine phosphorylation in murine sperm [PDF]

, 2016
Sperm capacitation is required for fertilization. At the molecular level, this process is associated with fast activation of protein kinase A. Downstream of this event, capacitating conditions lead to an increase in tyrosine phosphorylation. The identity
Alvau, Antonio, Battistone, Maria Agustina, Cuasnicu, Patricia Sara, Da Ros, Vanina Gabriela, Darszon, Alberto, De la Vega Beltran, José Luis, Gervasi, Maria Gracia, Greer, Peter, Krapf, Diego, Navarrete, Felipe A., Salicioni, Ana María, Sánchez Cárdenas, Claudia, Visconti, Pablo E., Xu, Xinran   +13 more
core   +1 more source

The cyclophilin A DIAGEOTROPICA gene affects auxin transport in both root and shoot to control lateral root formation [PDF]

, 2015
Cyclophilin A is a conserved peptidyl-prolyl cis-trans isomerase (PPIase) best known as the cellular receptor of the immunosuppressant cyclosporine A. Despite significant effort, evidence of developmental functions of cyclophilin A in non-plant systems ...
Azzarello, Elisa, Du, Yun-Long, Dubrovsky, Joseph G, Filichkin, Sergei, Friml, Jiri, Geisler, Markus, Ivanchenko, Maria G, Mancuso, Stefano, Medvecka, Eva, Megraw, Molly, Wang, Bangjun, Zhu, Jinsheng   +11 more
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Geothermal systems simulation: A case study [PDF]

, 2015
Geothermal reservoir simulation is a key step for developing sustainable and efficient strategies for the exploitation of geothermal resources. It is applied in the assessment of several areas of reservoir engineering, such as reservoir performance and ...
Guerrero-Martinez, Fernando J., Paul, Manosh, Verma, Surendra P., Younger, Paul L.   +3 more
core  

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source