Results 51 to 60 of about 6,865,105 (283)

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

Exponential Stability in Mean Square for Neutral Stochastic Partial Functional Differential Equations with Impulses

Journal of Applied Mathematics, 2013
We discuss the exponential stability in mean square of mild solution for neutral stochastic partial functional differential equations with impulses. By applying impulsive Gronwall-Bellman inequality, the stochastic analytic techniques, the fractional ...
Nan Ding
doaj   +1 more source

Square-mean global exponential stability of state variable x₂ of model (33).

, 2019
Square-mean global exponential stability of state variable x2 of model (33).
Tianwei Zhang (169823), Sufang Han (7148195), Guoxin Liu (1827139)   +2 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Stochastic Memristive Quaternion-Valued Neural Networks with Time Delays: An Analysis on Mean Square Exponential Input-to-State Stability

Mathematics, 2020
In this paper, we study the mean-square exponential input-to-state stability (exp-ISS) problem for a new class of neural network (NN) models, i.e., continuous-time stochastic memristive quaternion-valued neural networks (SMQVNNs) with time delays ...
Usa Humphries, Grienggrai Rajchakit, Pramet Kaewmesri, Pharunyou Chanthorn, Ramalingam Sriraman, Rajendran Samidurai, Chee Peng Lim   +6 more
doaj   +1 more source

On Symmetrized Stochastic Harmonically Convexity and Hermite–Hadamard Type Inequalities

Axioms, 2022
Throughout this study, the concept of symmetrized harmonically convex stochastic processes will be discussed in further detail. Some certain characterizations for symmetrized harmonically convex stochastic processes are discussed that use Hermite ...
Muhammad Amer Latif
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Stability Issues for Selected Stochastic Evolutionary Problems: A Review

Axioms, 2018
We review some recent contributions of the authors regarding the numerical approximation of stochastic problems, mostly based on stochastic differential equations modeling random damped oscillators and stochastic Volterra integral equations.
Angelamaria Cardone, Dajana Conte, Raffaele D’Ambrosio, Beatrice Paternoster   +3 more
doaj   +1 more source

Lyapunov stability analysis for nonlinear delay systems under random effects and stochastic perturbations with applications in finance and ecology

Advances in Difference Equations, 2021
This manuscript is involved in the study of stability of the solutions of functional differential equations (FDEs) with random coefficients and/or stochastic terms.
Abdulwahab Almutairi, H. El-Metwally, M. A. Sohaly, I. M. Elbaz   +3 more
doaj   +1 more source

Prescribed-Time Mean-Square Nonlinear Stochastic Stabilization

IFAC-PapersOnLine, 2020
Abstract We solve the prescribed-time mean-square stabilization problem, providing the first feedback solution to a stochastic null-controllability problem for strict-feedback nonlinear systems with stochastic disturbances. Our non-scaling backstepping design scheme’s key novel design ingredient is that, rather than employing “blowing up” time ...
Wuquan Li, Miroslav Krstic
openaire   +1 more source