Results 101 to 110 of about 18,531,799 (283)

APPLICATION OF DESCRIPTIVE STATISTICS METHODS IN CUSTOMS RISK ANALYSIS

open access: yesФинансы: теория и практика, 2017
Improving of risk management’s tools is one of the important ways of increasing the efficiency of customs control. A development of statistical methods to identify potential customs risks is the most promising area of research in this context.
O. E. Kudryavtsev, S. E. Tamrazyan
doaj  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Summing Modulo 2 of Stationary Binary Stochastic Processes

open access: yesIEEE Access
In the paper, we analyze the properties of the stochastic process obtained as the result of summing modulo 2 without carry of a finite number of stationary binary stochastic processes, some of which do not satisfy the independence condition.
Mieczyslaw Jessa, Jakub Nikonowicz
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Answering research questions without calculating the mean

open access: yesFrontiers in Psychology, 2015
Guillermo eCampitelli
doaj   +1 more source

Relationship Between Mean Faecal Gastrointestinal Nematode Egg Excretion in Horses and Its Variability: Implications for Control

open access: yesPathogens
Faecal egg counts (FECs) are used to assess the intensity of gastrointestinal nematode (GIN) infections in herbivores. FEC distribution is aggregated, meaning that approximately 20% of animals harbour 80% of infections.
Jacques Cabaret   +3 more
doaj   +1 more source

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