Results 91 to 100 of about 531,242 (294)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Least absolute deviation estimation of linear econometric models: A literature review [PDF]
Econometricians generally take for granted that the error terms in the econometric models are generated by distributions having a finite variance. However, since the time of Pareto the existence of error distributions with infinite variance is known ...
Dasgupta, Madhuchhanda, Mishra, SK
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
The absolute channel error (IED ratio) for the innervation zone detection (MEAN±SD). [PDF]
, 2016 The absolute channel error (IED ratio) for the innervation zone detection (MEAN±SD).
Hamid Reza Marateb (3569438) +4 more
core +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
Agricultural Cultivation Cost Prediction Using Neural Networks and Feature Importance Analysis
Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi)Agriculture is one of the most important sectors integral to human civilization, and technological adaptation is necessary to maintain its quality. This research aims to achieve high productivity in the agricultural sector by using neural networks or ...
Salmania Putri +2 more
doaj +1 more source
Another Look at Measures of Forecast Accuracy [PDF]
We discuss and compare measures of accuracy of univariate time series forecasts. The methods used in the M-competition and the M3-competition, and many of the measures recommended by previous authors on this topic, are found to be inadequate, and many of
Anne B. Koehler, Rob J. Hyndman
core
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Deep Neural Network-Driven Analysis of Free Vibrations in Tapered Beams
Applied MechanicsMost physical systems exhibit nonlinear behavior while in motion, making their resolution challenging due to nonlinearity, dynamic effects, and sensitivity to parameters such as frequency and amplitude. Traditional analytical and numerical approaches can
Jamshaid Ul Rahman +3 more
doaj +1 more source
IOP Conference Series: Materials Science and Engineering, 2018 Most existing Collaborative Filtering (CF) algorithms predict a rating as the preference of an active user toward a given item, which is always a decimal fraction. Meanwhile, the actual ratings in most data sets are integers. In this paper, we discuss and demonstrate why rounding can bring different influences to these two metrics; prove that rounding ...
Weijie Wang, Yanmin Lu
openaire +1 more source