Results 201 to 210 of about 5,121,571 (362)

Embedded positive constant r-mean curvature hypersurfaces in Mm × R

open access: yesAnais da Academia Brasileira de Ciências, 2005
Let M be an m-dimensional Riemannian manifold with sectional curvature bounded from below. We consider hypersurfaces in the (m + 1)-dimensional product manifold M x R with positive constant r-mean curvature.
Cheng Xu, Rosenberg Harold
doaj  

Red blood cells could protect miRNAs from degradation or loss thanks to Argonaute 2 binding

open access: yesFEBS Open Bio, EarlyView.
The present work investigates the presence and the stability of miRNAs into RBCs, both native and engineered. The observed stability is due to the Ago2 bound resulting in minimal RISC. Indeed, if the miRNA‐Ago2 complex is present, miRNAs are protected from release or degradation and they are biologically active. Thus, RBCs can act as miRNA carriers for
Elena Perla   +4 more
wiley   +1 more source

Ancient mean curvature flows with finite total curvature [PDF]

open access: yesarXiv
We construct an $I$-family of ancient graphical mean curvature flows over a minimal hypersurface in $\mathbb{R}^{n+1}$ of finite total curvature with the Morse index $I$ by establishing exponentially fast convergence in terms of $|x|^2-t$. As a corollary, we show that these ancient flows have finite total curvature and finite mass drop.
arxiv  

Dysfunctional tetraspanin 7 (TSP‐7) in Caenorhabditis elegans promotes; increases in average life‐ & health‐span, stress‐induced survival and motility

open access: yesFEBS Open Bio, EarlyView.
The C. elegans tetraspanin‐7 (tsp‐7) is a homologue of human CD63, which is a negative regulator of autophagy. The C. elegans strain, tm5761, has a dysfunctional (knockout) tsp‐7 gene. When compared to the wild‐type strain, the tm5761 strain shows increased: life‐ and health‐span; thermotolerance, and stress‐induced locomotion.
Brogan Jones   +2 more
wiley   +1 more source

Establishment and biological characterization of radioresistant colorectal cancer cell lines

open access: yesFEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu   +10 more
wiley   +1 more source

An enzyme‐linked immunosorbent assay (ELISA)‐based activity assay for AMP‐activated protein kinase (AMPK)

open access: yesFEBS Open Bio, EarlyView.
Measuring AMP‐activated protein kinase (AMPK) activity in vitro is crucial for testing AMPK activators or inhibitors with therapeutic potential. Here, we report an enzyme‐linked immunosorbent assay (ELISA)‐based AMPK activity assay with simple steps and high sensitivity, which offers a simple, robust, and cost‐effective alternative to traditional ...
Trezze P. Nguyen, Shangze Lyu, Yang Liu
wiley   +1 more source

Singularity of mean curvature flow with bounded mean curvature and Morse index [PDF]

open access: yesarXiv
We study the multiplicity of the singularity of mean curvature flow with bounded mean curvature and Morse index. For $3\leq n\leq 6$, we show that either the mean curvature or the Morse index blows up at the first singular time for a closed smooth embedded mean curvature flow in $\mathbb{R}^{n+1}$.
arxiv  

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