Results 151 to 160 of about 868,975 (356)

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1508-1516, May 2025.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang   +3 more
wiley   +1 more source

The Mean Curvature Flow in Minkowski Spaces [PDF]

open access: yesarXiv, 2017
Studying the geometric flow plays a powerful role in mathematics and physics. In this paper, we introduce the mean curvature flow on Finsler manifolds and give a number of examples of the mean curvature flow. For Minkowski spaces, a special case of Finsler manifolds, we will prove the existence and uniqueness for solution of the mean curvature flow and
arxiv  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu   +7 more
wiley   +1 more source

Eventual Regularization of Fractional Mean Curvature Flow [PDF]

open access: yesarXiv, 2019
We show that any open set that is a finite distance away from a Lipschitz subgraph will become a Lipschitz subgraph after flowing under fractional mean curvature flow for a finite, universal time. Our proof is quantitative and inherently nonlocal, as the corresponding statement is false for classical mean curvature flow.
arxiv  

The preservability of the curvature-adaptedness along the mean curvature flow [PDF]

open access: yesarXiv, 2020
In this paper, we investigate the preservability of the curvature-adaptedness along the mean curvature flow starting from a compact curvature-adapted hypersurface in locally symmetric spaces, where the curvature-adaptedness means that the shape operator and the normal Jacobi operator of the hypersurface commute.
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

CFD-based investigation of turbulent flow behavior in 90-deg pipe bends

open access: yesJournal of Applied Research in Technology & Engineering
This work investigated the influence of bend curvature on the parameters of turbulent flow through a 90° pipe bend using the numerical CFD method, implemented in ANSYS Fluent. The numerical predictions were validated to be in good agreement with existing
Rilwan Kayode Apalowo   +1 more
doaj   +1 more source

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