Results 91 to 100 of about 2,377,337 (300)

Mean IOP values ± standard deviation.

open access: yes, 2017
Mean IOP values ± standard deviation.
Norbert Pfeiffer (26543)   +4 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Multivariate L1 Statistical Methods: The Package MNM

open access: yesJournal of Statistical Software, 2011
In the paper we present an R package MNM dedicated to multivariate data analysis based on the L1 norm. The analysis proceeds very much as does a traditional multivariate analysis.
Klaus Nordhausen, Hannu Oja
doaj  

Subject characteristics (mean ± standard deviation).

open access: yes, 2018
Subject characteristics (mean ± standard deviation).
Emily E. Bechke (5932010)   +6 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

DECISION MAKING IN MINING INDUSTRY BASED ON THEORY OF GAMES WITH NATURE UNDER INTERVAL DATA

open access: yesГеотехнічна механіка
The need for decision-making is present in all areas of human activity (sociology, medicine, economics, military affairs, etc.). This is also extremely important in mining industry. Theory of games is widely used to support decision-making.
Yevhen Lapshyn, Oleksandr Shevchenko
doaj   +1 more source

Comparison of head-mounted perimeter (imo®) and Humphrey Field Analyzer

open access: yesClinical Ophthalmology, 2019
Tairo Kimura,1 Chota Matsumoto,2 Hiroki Nomoto2 1Department of Ophthalmology, Meiikai Ueno Eye Clinic, Tokyo, Japan; 2Department of Ophthalmology, Faculty of Medicine Osaka-Sayama City, Kindai University, Osaka, Japan Purpose: The head-mounted ...
Kimura T, Matsumoto C, Nomoto H
doaj  

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