Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Accuracy of seven three-dimensional facial scanning systems compared with cone-beam computed tomography: a pilot study. [PDF]
Dovhan A, Filonenko D, Palyvoda R.
europepmc +1 more source
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Within- and between-country variation in gestational age thresholds for retinopathy of prematurity screening in Latin America. [PDF]
Silva JC +11 more
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This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Investigating visual field measurements on perimetry and ganglion cell complex on optical coherence tomography in patients with suprasellar tumours. [PDF]
Gaibie S, Williams S.
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Correction: Pauzaite et al. Dbf4-Cdc7 (DDK) Inhibitor PHA-767491 Displays Potent Anti-Proliferative Effects via Crosstalk with the CDK2-RB-E2F Pathway. <i>Biomedicines</i> 2022, <i>10</i>, 2012. [PDF]
Pauzaite T +8 more
europepmc +1 more source
Estimating on-farm genotypic performance and variability using ranking data. [PDF]
Dorado-Betancourt H +8 more
europepmc +1 more source
Visual and refractive pattern in patients with comitant large angle esotropia. [PDF]
Khorrami-Nejad M +4 more
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Clinical application of unilateral intramedullary K-wire occupying technique for flexible reduction in pediatric supracondylar humeral fractures. [PDF]
Xu W +6 more
europepmc +1 more source

