Results 61 to 70 of about 2,138,244 (263)

Large deviation principle for the mean reflected stochastic differential equation with jumps

open access: yesJournal of Inequalities and Applications, 2018
In this paper, we establish a large deviation principle for a mean reflected stochastic differential equation driven by both Brownian motion and Poisson random measure. The weak convergence method plays an important role.
Yumeng Li
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

VAR Portfolio Optimal: Perbandingan Antara Metode Markowitz dan Mean Absolute Deviation

open access: yesJurnal Siasat Bisnis, 2009
Portfolio selection method which have been introduced by Harry Markowitz (1952) used variance or deviation standard as a measure of risk. Kanno and Yamazaki (1991) introduced another method and used mean absolute deviation as a measure of risk instead of
R. Agus Sartono, Arie Andika Setiawan
doaj   +4 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Multivariate L1 Statistical Methods: The Package MNM

open access: yesJournal of Statistical Software, 2011
In the paper we present an R package MNM dedicated to multivariate data analysis based on the L1 norm. The analysis proceeds very much as does a traditional multivariate analysis.
Klaus Nordhausen, Hannu Oja
doaj  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Entropy–Mean–Upper Partial Deviation–Absolute Deviation Portfolio Problem and Its Wasserstein Distributionally Robust Counterpart

open access: yesIEEE Access
This paper proposes an Entropy–Mean–Upper partial deviation–Absolute Deviation (EMUAD) portfolio problem, introducing entropy to reduce investment risk and enhance portfolio diversification while simultaneously considering metrics ...
Haonan Wang, Mingyang Fan, Bowen Liu
doaj   +1 more source

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