Results 161 to 170 of about 588,334 (347)

Triazine‐Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Novel photo‐clickable triazine‐trione thermosets can be shaped and cured under mild conditions, including room and physiological temperatures. These materials are biocompatible and support osteogenic differentiation of bone marrow–derived mesenchymal stem cells on their surface.
Åshild Johansen, Shuntaro Yamada, Daniel J. Hutchinson, Mohammed A. Yassin, Samih Mohamed‐Ahmed, Cecilie Gjerde, Michael Malkoch, Kamal Mustafa   +7 more
wiley   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

Advanced Healthcare Materials, EarlyView.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti, Salma Mansi, Dominic Biebl, Malin Reuter, Maximilian Grab, José Carlos Rodríguez‐Cabello, Petra Mela   +6 more
wiley   +1 more source

Injectable Stimuli‐Responsive Amphiphilic Hydrogel for Rapid Hemostasis, Robust Tissue Adhesion, and Controlled Drug Delivery in Trauma and Surgical Care

Advanced Healthcare Materials, EarlyView.
Fast‐acting hydrogel seals bleeding wounds as the illustrated injectable, pH‐responsive network rapidly gels in situ to stop hemorrhage, adhere strongly to wet tissue, and release antibiotics in a controlled, pH‐dependent manner. The material withstands high pressures, shows excellent biocompatibility, and degrades safely, offering a versatile platform
Arvind K. Singh Chandel, Runali Patil, Abrar Ali Khan, Deeksha Pandit, Kaushik Chatterjee, Maurice N. Collins   +5 more
wiley   +1 more source

Tunable Bioresorbable Scaffolds With Marine Sulfated Polysaccharides for Small‐Caliber Vascular Grafts: A Multi‐Layered Strategy Combining Electrospinning and 4‐Axis Printing

Advanced Healthcare Materials, EarlyView.
A multilayered small‐caliber vascular scaffold combining electrospinning and 4‐axis printing is developed and biofunctionalized with marine sulfated polysaccharides from Holothuria tubulosa. The resulting construct exhibits enhanced hemocompatibility, tunable mechanical properties, and supports endothelial and smooth muscle cell adhesion and ...
Gabriele Obino, Alberto Sensini, Tim ten Brink, Gabriele Nieddu, Tristan Bodet, Giovanni Andrea Deiana, Martijn van Griensven, Marilena Formato, Antonio J. Lepedda, Lorenzo Moroni   +9 more
wiley   +1 more source

An In Situ Embedded B‐MOF Sponge With Shape‐Memory for All‐in‐One Diabetic Wound Therapy

Advanced Healthcare Materials, EarlyView.
A smart shape‐memory sponge dressing (P1A3@B‐MOF) is developed for accelerated diabetic wound healing. It achieves pH‐responsive corelease of Zn2+ and salvianolic acid B, synergistically providing antibacterial action, repolarizing macrophages to the M2 phenotype, and promoting angiogenesis.
Hai Zhou, Chaoyang Huang, Yanqi Chen, Tingzi Zhao, Fengyi Zhu, Gong Jun, Jinrong Zhang, Yingsong Pan, Qiulan Wen, Lei Yang, Huihui Zhang, Lianglong Chen   +11 more
wiley   +1 more source

Directional Liquid Transport Enabled pH‐Responsive Hierarchical Composite for Enhanced Wound Healing

Advanced Healthcare Materials, EarlyView.
A hierarchical composite with a gradient architecture transitioning from hydrophobic to hydrophilic layers integrates diode‐like liquid transport, efficient water absorption, breathability, and mechanical robustness. This device enables a multifunctional therapeutic platform with pH‐responsive dual‐drug release, providing synergistic anti‐inflammatory ...
Baolin Wang, Li‐Fang Zhu, Yuna Lang, Siyi Zhang, Fei Chen, Ming‐Wei Chang   +5 more
wiley   +1 more source

Nb2C‐Reinforced Hydrogel Microneedle as Dual ROS‐Scavenging Platform to Promote Diabetic Wound Healing

Advanced Healthcare Materials, EarlyView.
An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng, Heyan Huang, Xiangru Chen, Jie Fu, Zhiwei Sun, Mengjuan Tao, Jianwei Mao, Fei Zhang, Zhou Wan, Yuan Li, Dingan Wu, Chuchao Zhou, Yanqing Yang   +12 more
wiley   +1 more source

Are neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and/or mean platelet volume (MPV) clinically useful as predictive parameters for preeclampsia?

Journal of Maternal-Fetal & Neonatal Medicine, 2019
D. Mannaerts, Suzanne Heyvaert, Chania De Cordt, C. Macken, Charlotte Loos, Y. Jacquemyn   +5 more
semanticscholar   +1 more source

Mean platelet volume/platelet count ratio in anemia

Platelets, 2012
Sun Young, Cho, John Jeongseok, Yang, Jin-Tae, Suh, Woo-In, Lee, Hee Joo, Lee, Tae Sung, Park   +5 more
openaire   +2 more sources