Results 91 to 100 of about 18,073,426 (243)

DNA ligase LigE increases bacterial transformation with damaged extracellular DNA

open access: yesFEBS Letters, EarlyView.
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan   +4 more
wiley   +1 more source

Ohio Governor's Residence and Heritage Garden

open access: yes
The mission of the Ohio Governor's Residence and Heritage Garden is to develop the Residence as a center of culture and education for Ohio, by documenting the history of the Residence and grounds; by the focused collecting and preserving of Ohio native ...

core   +1 more source

A continuous mashing plant controlled by mean residence time

open access: yes, 2023
Continuous processes offer more environmentally friendlier beer production compared to the batch production. However, the continuous production of mashing has not become state-of-the-art in the brewing industry.
Schneider, Jan   +9 more
core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Research on vitamin C loss prediction model of extruded kiwifruit pork jerky

open access: yesShipin yu jixie
[Objective] In order to explore the loss pattern of VC in kiwifruit pork jerky by twin-screw extrusion and solve the "black box" problem of nutrient loss during the extrusion process.
ZHANG Guangtao   +3 more
doaj   +1 more source

Twin Screw Granulation: An Investigation of the Effect of Barrel Fill Level

open access: yesPharmaceutics, 2018
This paper focuses on investigating the influence of varying barrel fill levels on the mean residence time, granule properties (median size, size distribution, and shape), and tensile strength of tablets.
Sushma V. Lute   +2 more
doaj   +1 more source

Numerical prediction of the mean residence time of solid materials in a pilot-scale rotary kiln

open access: yes, 2019
Five models that predict the Mean Residence Time (MRT) of solids in a rotary kiln are tested on three materials and validated experimentally. Furthermore, the influence of the kiln rotational speed and incline on the MRT was investigated.
Cuypers, Ann   +7 more
core   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Design and fabrication of a system to capture ambient CO2

open access: yesJournal of Air Pollution and Health
Introduction:In the coming decades, addressing climate change necessitates substantial Carbon dioxide (CO2) emission reductions. Carbon capture and storage are vital for achieving these goals.
Sagir Khan   +3 more
doaj   +1 more source

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