Results 201 to 210 of about 18,073,426 (243)
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Mean residence time in peripheral tissue
Journal of Pharmacokinetics and Pharmacodynamics, 1987The published methods for determining the mean residence time for drugs in peripheral tissue are reviewed in terms of assumptions involved, advantages and disadvantages. A method for determining mean transit time in peripheral tissue is proposed; this may be a more useful indicator of the tissue retention properties for drug compounds.
Joseph C Fleishaker, P J McNamara
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Mean Residence Time and Residence Time Distribution When Sawdust Is Dried in Continuous Dryers
Drying Technology, 2008Information on the mean residence time and the residence time distribution is of importance when optimizing a continuous dryer. In this study, an industrial method for determining the mean residence time is developed. The produced method is benchmarked on a laboratory scale against the stop-and-empty method.
Roger Renström
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Danckwerts’ law for mean residence time revisited
Chemical Engineering Science, 2006This paper shows that Danckwerts’ law for mean residence time in a vessel with continuous and steady through∞ow holds for a stochastic model based on a Markov chain for the particle spatial position, under a set of three very general conditions on the transfer probabilities.
Alex C. Hoffmann
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Comments on mean residence time determination
Journal of Pharmacokinetics and Biopharmaceutics, 1985In a recent paper, D. O. Chanter challenged the applicability of the use of statistical moments in estimating mean residence time and proposed an alternative approach. Errors in that paper are pointed out which involve the improper equating of whole-body amount of drug with plasma amount of drug in a kinetic system.
E M, Landaw, D, Katz
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The mean oceanic residence time
Marine Chemistry, 1982Abstract In this note the significance of heat of hydration and electronegativity in the study of oceanic residence times of elements is discussed.
Chen-Ping Chang +2 more
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Mean residence time in multicompartmental models with time delays
Journal of Biomedical Engineering, 1993Calculation of the mean residence time (MRT) of a drug in a stationary compartmental model is classically carried out from several expressions. Nevertheless, one or more time delays between compartments modify the mean residence times. It is the aim of this paper to propose a general method for MRT calculations, in any n-compartmental models which may ...
Y, Plusquellec, G, Houin
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Stratospheric mean residence time and mean age on the tropopause: Connections and implications for observational constraints [PDF]
Stratospheric mean residence time and mean age on the tropopause ΓΩ are shown to measure physically distinct aspects of stratospheric transport. Both ΓΩ and are mean transit times through the stratosphere of air that enters through tropopause region Ω
Francois Primeau +2 more
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On mean residence times in flow systems
Chemical Engineering Science, 1983Abstract A widely accepted result of residence time theory namely mean residence time is equal to the system volume divided by the flow rate was first offered by Danckwerts[l] and later extended by Buffham[21 and Gibilaro[3] to more general cases.
R.C. Awasthi, K. Vasudeva
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Mean residence time of plutonium in the troposphere
Environmental Science & Technology, 1982Plutonium is injected into the stratosphere by large atmospheric thermonuclear explosions. When aerosols bearing plutonium reenter the troposphere, they are removed by such processes as rainfall and sedimentation. In this work, the mean tropospheric residence time of stratospherically injected plutonium is calculated.
Robert W. Holloway, David W. Hayes
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Methods and findings in experimental and clinical pharmacology, 1986
The definition of mean residence time in the strict sense of mathematical statistics is deduced. It is demonstrated that the area-normalized concentration time curve is an estimate of the probability density function for residence times of drug molecules in the pharmacokinetic system, provided that the area under the concentration-time profile is ...
D, Brockmeier, H M, von Hattingberg
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The definition of mean residence time in the strict sense of mathematical statistics is deduced. It is demonstrated that the area-normalized concentration time curve is an estimate of the probability density function for residence times of drug molecules in the pharmacokinetic system, provided that the area under the concentration-time profile is ...
D, Brockmeier, H M, von Hattingberg
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