Results 51 to 60 of about 257,394 (299)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Documenting the location and magnitude of groundwater recharge is critical for understanding groundwater flow systems. Radioactive tracers, notably 14C, 3H, 36Cl, and the noble gases, together with other tracers whose concentrations vary over time, such ...
Karina Meredith +7 more
core +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and simulation of gas burner ejectors
Ignition within gas burner ejectors can lead to off design conditions and has significant influence on the burner behavior. Thus ignition in the ejector should be prevented. In the present study the influence of combustion reactions on the performance of
Mario Pichler +6 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Mean annual temperature and root carbon mean residence time (0–10 cm) of all sampling plots.
The curve displays the exponential relationship mean residence time (y) = 13.38 [1.94] * exp(-0.24 [0.05] * x), R2 = 0.53,P < 0.001. Values in square brackets are 1 SE.
Stefanie Meyer (159843) +5 more
core +1 more source
Hydrodynamic and solid residence time distribution in a circulating fluidized bed: experimental and 3D computational study [PDF]
Vertical profiles of local pressure, horizontal profiles of net vertical solid mass flux, and residence time distributions (RTD) of the solid phase are experimentally assessed in the riser of a small scale cold Circulating Fluidized Bed of 9 m high ...
Simonin, Olivier +3 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Estimation of Groundwater Mean Residence Time in Unconfined Karst Aquifers Using Recession Curves
A new parsimonious method is proposed to estimate the mean residence time of groundwater emerging at any specific time during recession periods from karst springs. The method is applicable to unconfined karstic aquifers with no-flow boundaries.
Kavousi, Alireza, Raeisi, Ezzat
core +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source

