Results 51 to 60 of about 259,559 (260)

Evidence‐Based Clinical Practice Guidelines for the Management of Pediatric Febrile Neutropenia: Resource‐Sensitive Recommendations for the Asian Continent

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Febrile neutropenia (FN) is a frequent and serious complication in children receiving cancer therapy. Standardizing FN management across Asia is challenging due to variable healthcare infrastructure, diagnostic capacity, and infection patterns; however, it could improve resource use and patient outcomes.
Joliza Patricia Cañeba   +29 more
wiley   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine   +21 more
wiley   +1 more source

Design and simulation of gas burner ejectors

open access: yesCarbon Resources Conversion, 2021
Ignition within gas burner ejectors can lead to off design conditions and has significant influence on the burner behavior. Thus ignition in the ejector should be prevented. In the present study the influence of combustion reactions on the performance of
Mario Pichler   +6 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Modeling the impacts of streambed sediment heterogeneity on hyporheic exchange

open access: yesShui kexue jinzhan, 2019
The hyporheic exchange plays a crucial role in maintaining fluvial ecological processes. In order to examine the influence of streambed heterogeneity on the hyporheic exchange,a surface water-groundwater coupling model is constructed for solving flow ...
CHEN Xiaobing, ZHENG Chunyang, YUAN Yue
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Factorial design to quantify the influence of extrusion parameters in the mean residence time

open access: yesPolímeros, 2010
Residence time distribution (RTD) is a very important parameter in extrusion, either for simple polymer processing or for special processes like compounding, blending, reactive compatibilization, and controlled degradation.
Tomás J. A. de Mélo   +2 more
doaj  

Mean sediment residence time in barchan dunes [PDF]

open access: yesJournal of Geophysical Research: Earth Surface, 2014
When a barchan dune migrates, the sediment trapped on its lee side is later mobilized when exposed on the stoss side. Then sand grains may undergo many dune turnover cycles before their ejection along the horns, but the amount of time a sand grain contributes to the dune morphodynamics remains unknown.
Zhang, D.   +3 more
openaire   +1 more source

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