Results 71 to 80 of about 250,845 (259)
Journal of Manufacturing and Materials ProcessingChemical mechanical polishing (CMP) is a widely used technique in semiconductor manufacturing to achieve a flat and smooth surface on silicon wafers.
Hafiz M. Irfan +4 more
doaj +1 more source
A physiological view and structures of mean residence times
General physiology and biophysics, 2014 The author's previous theoretical study described the determination of a physiologically realistic structure of a mean residence time of an intravenously administered drug (Ďurišová 2012). This study continues previous work and the aim is to determine physiologically realistic structures of mean residence times of a drug administered either orally ...
openaire +3 more sources
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Review: Axial Motion of Material in Rotary Kilns
EngThe article examines the parameters of axial motion of bulk material in rotary kilns, including bed height, axial velocity, and mean residence time.
Elmira Fedorova +3 more
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Mean Transit Time and Mean Residence Time for Linear Diffusion–Convection–Reaction Transport System [PDF]
Computational and Mathematical Methods in Medicine, 2007 Characteristic times for transport processes in biological systems may be evaluated as mean transit times (MTTs) (for transit states) or mean residence times (MRT) (for steady states). It is shown in a general framework of a (linear) reaction–diffusion–convection equation that these two times are related.
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
BMC Public Health, 2020 Background Greater travel time to cancer care has been identified as a potential barrier to care as well as associated with worse health outcomes. While rural cancer patients have been shown to travel farther for care, it is not known what patient ...
Joel E. Segel, Eugene J. Lengerich
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Enhancement of stability of metastable states in the presence of Lévy noise
SciPost PhysicsThe barrier-crossing event for superdiffusion characterized by symmetric Lévy flights is analyzed. Starting from the fractional Fokker-Planck equation, we derive an integro-differential equation along with the necessary conditions to calculate the mean ...
Alexander A. Dubkov, Claudio Guarcello, Bernardo Spagnolo
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source