Results 101 to 110 of about 10,620,708 (372)

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

open access: yesFEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu   +5 more
wiley   +1 more source

Robustness of mean-square exponential dichotomies for linear stochastic equations

open access: yesElectronic Journal of Differential Equations, 2017
We present the notion of mean-square exponential dichotomies for linear stochastic differential equations. We study the robustness of the mean-square exponential dichotomies, in the sense of the existence of a mean-square exponential dichotomy for a ...
Hailong Zhu, Yongxin Jiang
doaj  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Mean-square heterogeneous synchronization of interdependent networks with stochastic disturbances

open access: yesAdvances in Difference Equations, 2019
In this paper, the mean-square asymptotical heterogeneous synchronization of interdependent networks with stochastic disturbances, which is a zero-mean real Wiener process, is investigated.
Tianjiao Guo, Lilan Tu, Jiabo Chen
doaj   +1 more source

Exact Mean Integrated Squared Error

open access: yesThe Annals of Statistics, 1992
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Marron, J. S., Wand, M. P.
openaire   +3 more sources

Band limited image restoration by linear mean-square estimation [PDF]

open access: yes
Linear estimator optimum for data on finite interval for restoration of ...
Rino, C. L.
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Exploring novel antitubercular agents: Innovative design of 2,3-diaryl-quinoxalines targeting DprE1 for effective tuberculosis treatment

open access: yesOpen Chemistry
The rising instances of drug resistance in Mycobacterium tuberculosis strains pose a significant global health challenge. Conventional tuberculosis (TB) treatments, which typically involve multiple antibiotics, face hurdles like drug resistance, reduced ...
Sharma Kirti   +8 more
doaj   +1 more source

The Mean Square of the Hurwitz Zeta-Function in Short Intervals

open access: yesAxioms
The Hurwitz zeta-function ζ(s,α), s=σ+it, with parameter ...
Antanas Laurinčikas   +1 more
doaj   +1 more source

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