Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Quaternion Filtering Based on Quaternion Involutions and its Application in Signal Processing
The quaternion gradient plays an important role in quaternion signal processing, and has undergone several modifications. Recently, three methods for obtaining the quaternion gradient have been proposed based on generalized HR calculus, the quaternion ...
Gang Wang, Rui Xue
doaj +1 more source
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang +10 more
wiley +1 more source
Hardware-Based Calculation of Mean Square Error for Automatic Target Recognition in SAR Images
This paper presents a circuit architecture aiming for FPGA synthesis of a processing stage of an Automatic Target Recognition (ATR) algorithm to classify non-cooperative targets in Synthetic Aperture Radar (SAR) images using the SAMPLE database.
Lucas Urbanski +3 more
doaj +1 more source
The minimality of mean square error in chirp approximation using fractional fourier series and fractional fourier transform. [PDF]
Bafakeeh OT +9 more
europepmc +1 more source
A new approach to the credibility formula [PDF]
The usual credibility formula holds whenever, (i) claim size distribution is a member of the exponential family of distributions, (ii) prior distribution conjugates with claim size distribution, and (iii) square error loss has been considered. As long as,
Payandeh Najafabadi, Amir T.
core +1 more source
Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende +26 more
wiley +1 more source
Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher +10 more
wiley +1 more source
Nonlinear Distortion-Aware Channel Estimation Strategies for IRS-Aided MIMO Systems
The article addresses the challenges posed by nonlinear distortions in Intelligent Reflecting Surface (IRS)-assisted Multiple-Input Multiple-Output (MIMO) systems, which are often overlooked in conventional channel estimation strategies.
D. L. Sharini +3 more
doaj +1 more source
Bootstrapping the Mean Integrated Squared Error
Let \(X_ 1,\dots,X_ n\) be a sequence of i.i.d. real random variables from an unknown density \(f\). For a given kernel \(K\) and a bandwidth \(h>0\), denote with \(f_ h\) the associated Parzen-Rosenblatt estimator of \(f\). There exists a huge literature on how to choose \(h\) in an optimal way.
openaire +1 more source

