Advanced Materials, EarlyView.Bioorthogonal chemistry was applied to intracellularly photoactivate Doxorubicin (Dox) using gold nanostars (AuNSt) and near‐infrared (NIR) light. Two prodrugs were used: one photoactivatable, masked with 2‐nitrobenzyl carbamate (proDox1) and another photolabile, masked with 2‐nitrobenzyl diol (proDox2), which was attached to the AuNSt surface.
Juan José Esteve‐Moreno +15 more
wiley +1 more source
Minimization of proteome reallocation explains metabolic transition in hierarchical utilization of carbon sources. [PDF]
mSystemsLiu Z, Chen M, Hu J, Wang Y, Chen Y.
europepmc +1 more source
Radiation‐Resistant Aluminum Alloy for Space Missions in the Extreme Environment of the Solar System
Advanced Materials, EarlyView.A novel ultrafine‐grained aluminum crossover alloy exhibits unprecedented radiation resistance and mechanical stability under extreme irradiation doses up to 100 dpa. The exceptional resilience arises from thermodynamically stable T‐phase precipitates, enabling lightweight structural materials for next‐generation spacecraft and extraterrestrial ...
Patrick D. Willenshofer +9 more
wiley +1 more source
MOFSimBench: evaluating universal machine learning interatomic potentials in metal-organic framework molecular modeling. [PDF]
NPJ Comput MaterKraß H, Huang J, Moosavi SM.
europepmc +1 more source
Atomistic Mechanisms Triggered by Joule Heating Effects in Metallic Cu‐Bi Nanowires for Spintronics
Advanced Materials, EarlyView.Bi doped metallic Cu nanowires are promising for spintronics thanks to the stabilization of a giant spin Hall effect. However, heat resulting from current injection forces Bi to leave solution, forcing segregation into monoatomic decorations which evolve into coherent crystalline aggregates.
Alejandra Guedeja‐Marrón +6 more
wiley +1 more source
Molecular simulation-based 3D structural construction of olfactory receptor with agonist binding. [PDF]
J Comput Aided Mol DesHirao T +5 more
europepmc +1 more source
Advanced Materials, EarlyView.Multiphase printable organohydrogels with tunable microstructures are developed to control molecular transport pathways for immiscible cargo. The tortuosity and domain size of the colloidal phases are tuned by adjusting temperature and shear during processing, which enables the tailoring of diffusion kinetics due to different transport pathways.
Riley E. Dowdy‐Green +4 more
wiley +1 more source
Detailed in silico Evaluation of WNV Proteins: Dynamic and Thermodynamic Insights into Doravirine as a Potential Multitarget Agent. [PDF]
Drug Des Devel TherCurcio A +5 more
europepmc +1 more source
Porous Iridium Oxide Inverse Opal Catalysts Enable Efficient PEM Water Electrolysis
Advanced Materials, EarlyView.Porous iridium‐based inverse opal (IrOx‐IO) structures are introduced as high‐performance, unsupported PEM‐WE anode catalysts. Their electrochemical behavior is analyzed through porosity/surface area tuning, voltage breakdown, and circuit modeling.
Sebastian Möhle +4 more
wiley +1 more source
Research note: Exploring the effects of glycerol monolaurate on lipid metabolism in young broilers based on molecular dynamics simulation and 16S rRNA analysis. [PDF]
Poult SciZhang X, Pan X, Kong L, Song Z.
europepmc +1 more source