IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
FEBS Open Bio, EarlyView.To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
MEAN SQUARED ERRORS OF SMALL AREA ESTIMATORS UNDER A UNIT-LEVEL MULTIVARIATE MODEL [PDF]
This work deals with estimating the vector of means of characteristics of small areas. In this context, a unit level multivariate model with correlated sampling errors is considered.
Isabel Molina, Amparo Baillo
core
Bootstrap prediction mean squared errors of unobserved states based on the Kalman filter with estimated parameters [PDF]
, 2010 Prediction intervals in State Space models can be obtained by assuming Gaussian innovations and using the prediction equations of the Kalman filter, where the true parameters are substituted by consistent estimates.
Ruiz Ortega, Esther +2 more
core +1 more source
Mathematical and Computational ApplicationsAccurate housing price prediction is important for market efficiency and purchasing decisions. However, multicollinearity among independent variables remains a major challenge in linear regression, causing variance inflation and reducing the reliability ...
Osman Ufuk Ekiz, Meltem Ekiz
doaj +1 more source
Rule-Based Neutrosophic Triplet Refined Interval-Valued Data Partition Analyzing The Movement of Stock Market Price [PDF]
Neutrosophic Sets and SystemsThis study introduces an innovative approach to analysing stock market index movements through a RuleBased Neutrosophic Triplet Refined Interval-Valued Data Partition (NTRIVDP) model.
S. Bhuvaneswari +2 more
doaj +1 more source
Design-based properties of the nearest neighbor spatial interpolator and its bootstrap mean squared error estimator. [PDF]
Biometrics, 2022 Fattorini L +3 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Mean Squared Error Averaged Across Subjects.
, 2013 The results of four separate models run against all experiments in DREAM. The Mean Squared Error (+/− STD) averaged across subjects for each experiment is reported.
Ben Walker (484674) +1 more
core +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Annals of Clinical and Translational Neurology, EarlyView.Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source