Results 41 to 50 of about 6,320,755 (303)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Information, Meaning and Eigenforms: In the Light of Sociology, Agent-Based Modeling and AI

open access: yesInformation, 2012
The paper considers the relation of Shannon-type information to those semantic and hermeneutic aspects of communication, which are often referred to as meaning. It builds on considerations of Talcott Parsons, Niklas Luhmann and Robert K.
Manfred Füllsack
doaj   +1 more source

Meaning of the wave function [PDF]

open access: yes, 2010
We investigate the meaning of the wave function by analyzing the mass and charge density distributions of a quantum system. According to protective measurement, a charged quantum system has mass and charge density distributing in space, proportional to ...
Adler   +45 more
core   +6 more sources

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson   +3 more
wiley   +1 more source

Leisure and meaning in life

open access: yesFrontiers in Psychology, 2023
How people engage in leisure is an important but frequently underappreciated aspect of meaning in life. Leisure activities range from highly engaging and meaningful to subjectively trivial.
Seppo E. Iso-Ahola, Roy F. Baumeister
doaj   +1 more source

Does Meaning Evolove? [PDF]

open access: yes, 2004
A common method of improving how well understood a theory is, is by comparing it to another theory which has been better developed. Radical interpretation is a theory which attempts to explain how communication has meaning.
D.Roberts, Mark
core  

Evaluating the Utility of Paired Tumor and Germline Targeted DNA Sequencing for Pediatric Oncology Patients: A Single Institution Report

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate the diagnostic yield and utility of universal paired tumor–normal multigene panel sequencing in newly diagnosed pediatric solid and central nervous system (CNS) tumor patients and to compare the detection of germline pathogenic/likely pathogenic variants (PV/LPVs) against established clinical referral criteria for cancer ...
Natalie Waligorski   +9 more
wiley   +1 more source

Daffodils and Solitude in William Wordsworth’s I Wandered Lonely as A Cloud

open access: yesBuletin Al-Turas, 2023
Purpose This study aims to identify the meaning of Wordsworth’s poem entitled I Wandered Lonely as a Cloud by analyzing its intrinsic elements.   Method The present study is qualitative interpretive, focusing on the meaning conveyed in the poem ...
Ni Komang Arie Suwastini   +1 more
doaj   +1 more source

The Meaning of Animals [PDF]

open access: yes, 2005
This research examines the social construction of animals by a rural Allegheny culture using a linguistic approach based on estimating the set of attributes associated with the words they used to describe animals.
Lawson, Helene M   +2 more
core  

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