Results 131 to 140 of about 115,279,540 (302)

Sense of meaning in life and self-esteem in Forensic Psychiatric Patients

open access: yesJournal of Modern Science
Objectives This study aimed to assess the levels of meaning in life and self-esteem among mentally disordered offenders hospitalized in forensic psychiatric units.
Grzegorz Andrzej Kudlak   +2 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Future orientation and meaning in life in late-adolescents during the experience of COVID-19 restriction: Italy-Mexico comparison

open access: yes, 2022
Our hypothesis is that the pandemic, as the set of these exceptional conditions concerning some specific developmental tasks, has caused in young people the appearance of internalizing symptoms (anxiety, depression and stress) related to their time ...
Santa Parrello   +2 more
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Depression vs. Neuroticism, the Relationships with Past and Present Life Satisfaction and Presence of Meaning in Life [PDF]

open access: yesمجله علوم روانشناختی
Background: Adulthood, especially old age, Lifestyle and spiritual vitality can play a role as factors influencing Alzheimer's disorder in this age period.
Maryamsadat Mirpour   +3 more
doaj  

The relation of the attitude dimensions to prayer with the life satisfaction and meaning in life in female students of Qayen high school

open access: yesFiyz̤, 2020
Background: This research aims to study the relation of the attitude dimensions to prayer whit life satisfaction and meaning in life in female students of Qayen high school. Materials and Methods: In this cross-analytical study, 285 female students were
Ahmad Movahed   +2 more
doaj  

Quantifying the “Meaning of Life” [PDF]

open access: yesJournal of the American Academy of Audiology, 2020
openaire   +2 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Death and the Meaning of Life : A Critical Study of Metz’s Meaning in Life

open access: yes, 2015
In Meaning in Life: An Analytic Study, Thaddeus Metz advocates a kind of naturalistic objective theory of meaning in life, through a rejection of supernaturalism.
Yoshizawa, Fumitake
core  

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