Results 41 to 50 of about 506,706 (314)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

A Person-Centered Analysis of Meaning in Life, Purpose Orientations, and Attitudes toward Life among Chinese Youth

open access: yesBehavioral Sciences, 2023
Background: Meaning in life, purpose orientations, and attitudes toward life have a significant impact on youths’ well-being. The purpose of this study is to investigate the developmental trends of youths’ meaning in life, purpose orientations, and ...
Hong Wang, Xiaosong Gai, Songliang Li
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Increased Risk of Sarcomas in Children With Congenital Anomalies: Findings From the Genetic Overlap Between Anomalies and Cancer in Kids (GOBACK) Registry Linkage Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters   +17 more
wiley   +1 more source

Purpose Orientation and Its Protective Effect on Self-Esteem Among Chinese Depressive Patients: A Comparative Study

open access: yesPsychology Research and Behavior Management, 2023
Dannuo Lyu,1 Xiaosong Gai,1,2 Yanfeng Zhong3 1School of Psychology, Northeast Normal University, Changchun, Jilin Province, People’s Republic of China; 2Research Center of Mental Health Education in Northeast Normal University, Key Research Institute of ...
Lyu D, Gai X, Zhong Y
doaj  

The Meaning of Life Among Caregivers [PDF]

open access: bronze, 2021
Inna Rozentsvit
openalex   +1 more source

EVOLUTION AND THE MEANING OF LIFE

open access: yesZygon: Journal of Religion and Science, 1987
Abstract. The last century has witnessed a succession of revolutionary transformations in the discipline of biology. However, the rapid expansion of our understanding of life and its nature has had curiously little impact on the way that questions about life and its significance have been discussed by philosophers.
openaire   +3 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Beliefs in Miraculous Healings, Religiosity and Meaning in Life

open access: yesReligions, 2015
Throughout centuries, many interpretations of miraculous healings have been offered by philosophers, theologians, physicians and psychologists. Different approaches to miracles originate from the differences in understanding of causative factors ...
Jakub Pawlikowski   +3 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

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